Idiopathic Papular Dermatitis in the Spectrum of Chronic Papular Eruptions (Subacute Prurigo): Reappraisal and Diagnostic Algorithm.
Academic Medical Centers
Adult
Age Distribution
Aged
Aged, 80 and over
Algorithms
Biopsy, Needle
Chronic Disease
Cohort Studies
Dermatitis
/ epidemiology
Female
Humans
Immunohistochemistry
Male
Middle Aged
Prevalence
Prognosis
Prurigo
/ epidemiology
Retrospective Studies
Severity of Illness Index
Sex Distribution
Surveys and Questionnaires
Tertiary Care Centers
United States
Dermatitis
Idiopathic papular dermatitis
Papular eruptions
Journal
Dermatology (Basel, Switzerland)
ISSN: 1421-9832
Titre abrégé: Dermatology
Pays: Switzerland
ID NLM: 9203244
Informations de publication
Date de publication:
2019
2019
Historique:
received:
02
11
2018
accepted:
31
12
2018
pubmed:
6
3
2019
medline:
18
12
2019
entrez:
6
3
2019
Statut:
ppublish
Résumé
The clinical diagnosis of papular eruptions is common but poorly characterized in the literature and the etiology is often unknown. To characterize the entity of idiopathic papular dermatitis in the spectrum of chronic papular eruptions. The cohort consisted of patients who presented at a tertiary medical center in 2005-2014 with a papular eruption of at least 4 months' duration. Findings on histological analysis and thorough clinical investigation, performed in all cases, were collected. The patients completed a questionnaire on disease course and outcome. Sixty-five patients were included. Sixteen patients showed morphological changes over time and were excluded. Investigations in the remaining 49 patients with a consistent papular morphology yielded a well-defined diagnosis in 23 (46%). Twenty-six patients (54%; 14 male) were diagnosed with idiopathic papular dermatitis. Their mean age at onset was 61.6 ± 14.4 years and the mean duration of disease 3.11 ± 2.726 years. In 60%, the rash resolved with conservative treatment during follow-up (mean 4.35 ± 2.53 years). Chronic papular eruptions encompass a wide range of skin diseases. In more than half of the cases, the etiopathogenesis remains unclear. On the basis of our results, we propose a diagnostic algorithm for idiopathic papular dermatitis.
Sections du résumé
BACKGROUND
BACKGROUND
The clinical diagnosis of papular eruptions is common but poorly characterized in the literature and the etiology is often unknown.
OBJECTIVE
OBJECTIVE
To characterize the entity of idiopathic papular dermatitis in the spectrum of chronic papular eruptions.
METHODS
METHODS
The cohort consisted of patients who presented at a tertiary medical center in 2005-2014 with a papular eruption of at least 4 months' duration. Findings on histological analysis and thorough clinical investigation, performed in all cases, were collected. The patients completed a questionnaire on disease course and outcome.
RESULTS
RESULTS
Sixty-five patients were included. Sixteen patients showed morphological changes over time and were excluded. Investigations in the remaining 49 patients with a consistent papular morphology yielded a well-defined diagnosis in 23 (46%). Twenty-six patients (54%; 14 male) were diagnosed with idiopathic papular dermatitis. Their mean age at onset was 61.6 ± 14.4 years and the mean duration of disease 3.11 ± 2.726 years. In 60%, the rash resolved with conservative treatment during follow-up (mean 4.35 ± 2.53 years).
CONCLUSIONS
CONCLUSIONS
Chronic papular eruptions encompass a wide range of skin diseases. In more than half of the cases, the etiopathogenesis remains unclear. On the basis of our results, we propose a diagnostic algorithm for idiopathic papular dermatitis.
Identifiants
pubmed: 30836368
pii: 000496540
doi: 10.1159/000496540
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
205-212Informations de copyright
© 2019 S. Karger AG, Basel.