Global Genetics Research in Prostate Cancer: A Text Mining and Computational Network Theory Approach.

biomedical text mining computational network theory genetics meta-analysis natural language processing network science prostate cancer text mining

Journal

Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621

Informations de publication

Date de publication:
2019
Historique:
received: 21 07 2018
accepted: 28 01 2019
entrez: 7 3 2019
pubmed: 7 3 2019
medline: 7 3 2019
Statut: epublish

Résumé

Prostate cancer is the most common cancer type in men in Finland and second worldwide. In this paper, we analyze almost 150, 000 published papers about prostate cancer, authored by ten thousands of scientists worldwide, with an integrated text mining and computational network theory approach. We demonstrate how to integrate text mining with network analysis investigating research contributions of countries and collaborations within and between countries. Furthermore, we study the time evolution of individually and collectively studied genes. Finally, we investigate a collaboration network of Finland and compare studied genes with globally studied genes in prostate cancer genetics. Overall, our results provide a global overview of prostate cancer research in genetics. In addition, we present a specific discussion for Finland. Our results shed light on trends within the last 30 years and are useful for translational researchers within the full range from genetics to public health management and health policy.

Identifiants

pubmed: 30838019
doi: 10.3389/fgene.2019.00070
pmc: PMC6383410
doi:

Types de publication

Journal Article

Langues

eng

Pagination

70

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Auteurs

Md Facihul Azam (MF)

Predictive Society and Data Analysis Lab, Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland.
Institute of Biosciences and Medical Technology, Tampere, Finland.

Aliyu Musa (A)

Predictive Society and Data Analysis Lab, Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland.
Institute of Biosciences and Medical Technology, Tampere, Finland.

Matthias Dehmer (M)

Faculty for Management, Institute for Intelligent Production, University of Applied Sciences Upper Austria, Steyr, Austria.
Department of Mechatronics and Biomedical Computer Science, UMIT, Hall in Tyrol, Austria.
College of Computer and Control Engineering, Nankai University, Tianjin, China.

Olli P Yli-Harja (OP)

Institute of Biosciences and Medical Technology, Tampere, Finland.
Computational Systems Biology, Faculty of Biomedical Engineering, Tampere University, Tampere, Finland.
Institute for Systems Biology, Seattle, WA, United States.

Frank Emmert-Streib (F)

Predictive Society and Data Analysis Lab, Faculty of Information Technology and Communication Sciences, Tampere University, Tampere, Finland.
Institute of Biosciences and Medical Technology, Tampere, Finland.

Classifications MeSH