McKittrick-Wheelock Syndrome Presenting with Acute Kidney Injury and Metabolic Alkalosis: Case Report and Narrative Review.


Journal

Case reports in gastrointestinal medicine
ISSN: 2090-6528
Titre abrégé: Case Rep Gastrointest Med
Pays: United States
ID NLM: 101580185

Informations de publication

Date de publication:
2019
Historique:
received: 25 10 2018
accepted: 09 01 2019
entrez: 7 3 2019
pubmed: 7 3 2019
medline: 7 3 2019
Statut: epublish

Résumé

A rare combination of severe volume depletion and electrolyte imbalance caused by a rectal villous adenoma is often referred to as the McKittrick-Wheelock syndrome. Patients usually seek medical care because of chronic hypersecretory diarrhea and display renal failure, metabolic acidosis, hyponatremia, and hypokalemia. We report the case of a 68-year-old woman who presented with this condition but showed unusual features such as severe hypokalemia and metabolic alkalosis, without diarrhea. She subsequently underwent transanal endoscopic microsurgery (TEMS), an innovative procedure in the management of large rectal adenomas. We also provide a narrative review of the literature on this rare entity.

Identifiants

pubmed: 30838142
doi: 10.1155/2019/3104187
pmc: PMC6374786
doi:

Types de publication

Case Reports

Langues

eng

Pagination

3104187

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Auteurs

Mireille Caron (M)

Faculty of Medicine, Laval University, Québec City, QC, Canada.

Charles-Etienne Dubrûle (CE)

Department of Internal Medicine, CHU de Québec, Québec City, QC, Canada.

François Letarte (F)

Department of Surgery, CHU de Québec, Québec City, QC, Canada.

Valéry Lemelin (V)

Department of Gastroenterology, CHU de Québec, Québec City, QC, Canada.

Alexandre Lafleur (A)

Department of Internal Medicine, CHU de Québec, Québec City, QC, Canada.
Faculty of Medicine, Department of Medicine, Laval University, Québec City, QC, Canada.

Classifications MeSH