Salivary alkaline phosphatase activity and chronological age as indicators for skeletal maturity.
Alkaline phosphatase
Biomarker
Chronological
Orthodontics
Saliva
Skeletal maturation
Journal
The Angle orthodontist
ISSN: 1945-7103
Titre abrégé: Angle Orthod
Pays: United States
ID NLM: 0370550
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
pubmed:
7
3
2019
medline:
4
1
2020
entrez:
7
3
2019
Statut:
ppublish
Résumé
To investigate the relationship between salivary alkaline phosphatase activity (ALP), protein concentration, and chronological age with cervical vertebral maturation stages (CVMS) as noninvasive biomarkers for skeletal maturity assessment. This cross-sectional study included 79 subjects (48 females, 31 males; 7 to 23 years old) categorized into five CVMS based on lateral cephalographs evaluated by three examiners. ALP activity and protein concentration in unstimulated whole saliva were compared among five CVMS. The association between age and CVMS was assessed and five multinomial logistic regression models were utilized to predict CVMS based on salivary ALP activity, protein concentration, and chronological age. Salivary ALP reached the peak at early pubertal stage and then declined with a significant difference between CVMS I and CVMS II ( The combination of salivary ALP activity and chronological age may provide the best CVMS prediction.
Identifiants
pubmed: 30840495
doi: 10.2319/030918-197.1
pmc: PMC8117189
doi:
Substances chimiques
Biomarkers
0
Alkaline Phosphatase
EC 3.1.3.1
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
637-642Références
Angle Orthod. 2012 Nov;82(6):1047-52
pubmed: 22691035
Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):484.e1-6; discussion 484-5
pubmed: 19815140
Am J Orthod Dentofacial Orthop. 2009 Oct;136(4):501-9
pubmed: 19815151
Eur J Orthod. 2001 Dec;23(6):715-31
pubmed: 11890067
Am J Orthod Dentofacial Orthop. 2008 Aug;134(2):209-16
pubmed: 18675202
Am J Orthod Dentofacial Orthop. 1990 Jul;98(1):33-40
pubmed: 2363404
J Clin Periodontol. 1996 Jun;23(6):587-94
pubmed: 8811480
J Clin Res Pediatr Endocrinol. 2011;3(1):7-11
pubmed: 21448327
Dent Res J (Isfahan). 2015 Sep-Oct;12(5):443-8
pubmed: 26604958
Biometrics. 1977 Mar;33(1):159-74
pubmed: 843571
Am J Orthod Dentofacial Orthop. 2013 Apr;143(4):515-21
pubmed: 23561413
J Clin Endocrinol Metab. 1997 Jul;82(7):2056-61
pubmed: 9215272
Gaoxiong Yi Xue Ke Xue Za Zhi. 1989 Jul;5(7):389-97
pubmed: 2810445
Angle Orthod. 2004 Feb;74(1):118-24
pubmed: 15038500
Am J Orthod Dentofacial Orthop. 2006 Nov;130(5):662-5
pubmed: 17110265
Orthod Craniofac Res. 2011 Feb;14(1):44-50
pubmed: 21205168
Open Dent J. 2016 Apr 08;10:99-108
pubmed: 27335610
J Proteome Res. 2009 Aug;8(8):4126-34
pubmed: 19591489
Clin Chem. 1977 Mar;23(3):469-72
pubmed: 837534
Angle Orthod. 2012 Nov;82(6):1123-31
pubmed: 22417653
Angle Orthod. 2002 Aug;72(4):316-23
pubmed: 12169031
Psychoneuroendocrinology. 2004 Feb;29(2):125-40
pubmed: 14604596