Feasibility of Home-Based Automated Assessment of Postural Instability and Lower Limb Impairments in Parkinson's Disease.
Parkinson’s disease
RGB-depth
UPDRS tasks
at-home monitoring
automated assessment
center of mass
machine learning
movement disorders
neurorehabilitation
postural stability
posture
Journal
Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366
Informations de publication
Date de publication:
05 Mar 2019
05 Mar 2019
Historique:
received:
28
12
2018
revised:
01
02
2019
accepted:
26
02
2019
entrez:
8
3
2019
pubmed:
8
3
2019
medline:
30
4
2019
Statut:
epublish
Résumé
A self-managed, home-based system for the automated assessment of a selected set of Parkinson's disease motor symptoms is presented. The system makes use of an optical RGB-Depth device both to implement its gesture-based human computer interface and for the characterization and the evaluation of posture and motor tasks, which are specified according to the Unified Parkinson's Disease Rating Scale (UPDRS). Posture, lower limb movements and postural instability are characterized by kinematic parameters of the patient movement. During an experimental campaign, the performances of patients affected by Parkinson's disease were simultaneously scored by neurologists and analyzed by the system. The sets of parameters which best correlated with the UPDRS scores of subjects' performances were then used to train supervised classifiers for the automated assessment of new instances of the tasks. Results on the system usability and the assessment accuracy, as compared to clinical evaluations, indicate that the system is feasible for an objective and automated assessment of Parkinson's disease at home, and it could be the basis for the development of neuromonitoring and neurorehabilitation applications in a telemedicine framework.
Identifiants
pubmed: 30841656
pii: s19051129
doi: 10.3390/s19051129
pmc: PMC6427119
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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