Retinal oximetry in normal and amblyopic children: a pilot study.
amblyopia
retinal oximetry
Journal
Acta ophthalmologica
ISSN: 1755-3768
Titre abrégé: Acta Ophthalmol
Pays: England
ID NLM: 101468102
Informations de publication
Date de publication:
Nov 2019
Nov 2019
Historique:
received:
15
06
2018
accepted:
02
02
2019
pubmed:
8
3
2019
medline:
6
2
2020
entrez:
8
3
2019
Statut:
ppublish
Résumé
To study the retinal vascular oxygen saturation in amblyopic eyes and compare them to unaffected fellow eyes and eyes of normal subjects. A total of 32 amblyopic, 24 normal and 13 fellow eyes of patients below age of 18 were enrolled in this prospective observation study. Retinal oximetry was performed using the Oxymap T1 retinal oximeter. Retinal vascular oxygen saturations and diameters were compared between amblyopic eyes, normal eyes and unaffected fellow eyes. The average age was 8.6 years in the amblyopia group (M:F 16:16) and 10.9 years in the normal group (M:F 7:5; p = 0.024). Median corrected distance visual acuity in the amblyopia group was 20/50; it was 20/20 in the other groups (p < 0.001). The average arteriolar and venous saturation in the amblyopia, normal and fellow group was 84.5% (95% CI: 82.6-86.4), 83.2% (95% CI: 80.7-85.6) and 80.8% (95% CI: 78.6-82.9) and 51.9% (95% CI: 50.4-53.4), 50.8% (95% CI: 48.2-53.4) and 49.3% (95% CI: 45.7-52.9). There was no statistically significant difference between the saturation values of the amblyopia group and the controls, however, significantly higher values were found in the amblyopia group compared to the fellow group for arteriolar and venous saturations (p = 0.013; p = 0.005). Arteriolar and venous diameters showed no significant difference between groups. Amblyopic eyes showed higher mean oxygen saturations than the fellow eyes. This observation could be due to altered neuronal activity or could be due to a measurement artefact due to alterations in retinal reflectivity.
Substances chimiques
Oxygen
S88TT14065
Types de publication
Comparative Study
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
684-687Informations de copyright
© 2019 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
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