Postoperative Clinical Monitoring After Morphine Administration: A Retrospective Multicenter Practice Survey.


Journal

Current drug safety
ISSN: 2212-3911
Titre abrégé: Curr Drug Saf
Pays: United Arab Emirates
ID NLM: 101270895

Informations de publication

Date de publication:
2019
Historique:
received: 31 12 2018
revised: 21 02 2019
accepted: 25 02 2019
pubmed: 8 3 2019
medline: 7 1 2020
entrez: 8 3 2019
Statut: ppublish

Résumé

The objective of this survey was to describe the clinical monitoring practically used after intravenous, subcutaneous or neuraxial (epidural or intrathecal) administration of morphine. It was a descriptive, retrospective, multicenter (10 hospitals) survey based on the medical charts' analysis, which evaluated the postoperative clinical monitoring after morphine administration. Morphine was delivered intravenously (69%), intrathecally (19%), epidurally (10%) and/or subcutaneously (12%). Clinical monitoring protocols and protocols for the management of side effects were both present in 60% (n=6/10), only one of the two types of protocols in 10% (n=1/10) and both absent in 30% (n=3/10). Protocols for the management of respiratory depression and consciousness evaluation were present in 70% of cases (n=7/10). These events were reported on medical records without any prescription or protocol in 35% (n=14/40) and 37,5% (n=15/40) respectively. Prescriptions for respiratory rate evaluation and clinical monitoring of consciousness were in agreement with only 20% of the medical data and medical records. Different levels of respiratory rate were observed: 43% (n=3/7) below 8/min, 43% (n=3/7) below 10/min and 14% (n=1/7) below 12/min. Clinical monitoring was not performed in 31% (n=31/100) for consciousness and in 35% (n=35/100) for respiratory rate. Pulse oximeter was used in 48% (n=48/100) of patients. Capnography was never used. Respiratory depression occurred in 1% (n=1/100) of cases. This survey emphasizes an important disparity in the prescription of medical monitoring and a lack of use of protocols when morphine is administered. It demonstrates the need for a standardization of protocols according to the existing guidelines.

Sections du résumé

BACKGROUND BACKGROUND
The objective of this survey was to describe the clinical monitoring practically used after intravenous, subcutaneous or neuraxial (epidural or intrathecal) administration of morphine.
METHODS METHODS
It was a descriptive, retrospective, multicenter (10 hospitals) survey based on the medical charts' analysis, which evaluated the postoperative clinical monitoring after morphine administration.
RESULTS RESULTS
Morphine was delivered intravenously (69%), intrathecally (19%), epidurally (10%) and/or subcutaneously (12%). Clinical monitoring protocols and protocols for the management of side effects were both present in 60% (n=6/10), only one of the two types of protocols in 10% (n=1/10) and both absent in 30% (n=3/10). Protocols for the management of respiratory depression and consciousness evaluation were present in 70% of cases (n=7/10). These events were reported on medical records without any prescription or protocol in 35% (n=14/40) and 37,5% (n=15/40) respectively. Prescriptions for respiratory rate evaluation and clinical monitoring of consciousness were in agreement with only 20% of the medical data and medical records. Different levels of respiratory rate were observed: 43% (n=3/7) below 8/min, 43% (n=3/7) below 10/min and 14% (n=1/7) below 12/min. Clinical monitoring was not performed in 31% (n=31/100) for consciousness and in 35% (n=35/100) for respiratory rate. Pulse oximeter was used in 48% (n=48/100) of patients. Capnography was never used. Respiratory depression occurred in 1% (n=1/100) of cases.
CONCLUSION CONCLUSIONS
This survey emphasizes an important disparity in the prescription of medical monitoring and a lack of use of protocols when morphine is administered. It demonstrates the need for a standardization of protocols according to the existing guidelines.

Identifiants

pubmed: 30843492
pii: CDS-EPUB-97088
doi: 10.2174/1574886314666190306110434
doi:

Substances chimiques

Analgesics, Opioid 0
Morphine 76I7G6D29C

Types de publication

Clinical Trial Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

140-146

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Julien Raft (J)

Department of Anesthesiology and Pain Medicine, University of Montreal, Maisonneuve-Rosemont Hospital, 5415 Boulevard de l'Assomption, Montreal, QC H1T2M4, Canada.

Kévin Podrez (K)

Department of Anesthesiology and Intensive Care, University Hospital of Nancy, 29, avenue du Marechal-de-Lattre-de-Tassigny, 54035 Nancy Cedex, France.

Cédric Baumann (C)

Clinical Research Support Facility PARC, UMDS, University Hospital of Nancy, Vandoeuvre-les-Nancy, France.

Philippe Richebé (P)

Department of Anesthesiology and Pain Medicine, University of Montreal, Maisonneuve-Rosemont Hospital, 5415 Boulevard de l'Assomption, Montreal, QC H1T2M4, Canada.

Hervé Bouaziz (H)

Department of Anesthesiology and Intensive Care, University Hospital of Nancy, 29, avenue du Marechal-de-Lattre-de-Tassigny, 54035 Nancy Cedex, France.

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Classifications MeSH