Surface engineering of LENS-Ti-6Al-4V to obtain nano- and micro-surface topography for orthopedic application.


Journal

Nanomedicine : nanotechnology, biology, and medicine
ISSN: 1549-9642
Titre abrégé: Nanomedicine
Pays: United States
ID NLM: 101233142

Informations de publication

Date de publication:
06 2019
Historique:
received: 27 10 2018
revised: 13 02 2019
accepted: 13 02 2019
pubmed: 8 3 2019
medline: 4 12 2019
entrez: 8 3 2019
Statut: ppublish

Résumé

Two distinct surface topographies consisting of micro- and nano-surface were developed using laser texturing (LT) and anodization process respectively and their effect on the surface-related properties of Ti-6Al-4V fabricated using Laser Engineered Net Shaping (LENS) were determined. The topographies developed using laser texturing (25, 50 and 75% overlap) were examined using 3D profilometer, whereas, Field Emission Scanning Electron Microscopy (FE-SEM) was used to analyze Titania NanoTubes (TNT) formed using anodization. Though all the surface modified specimens exhibited hydrophilic behavior, least contact angle values were observed for the specimen surface modified with TNT. 25LT and 50LT specimens offered about 8 fold higher corrosion resistance than TNT specimens. All the surface modified samples exhibited non-toxicity to blood cells as well as to the mesenchymal stem cells (hMSCs) with a higher rate of proliferation and differentiation hMSCs observed on 75LT specimens and TNT specimen.

Identifiants

pubmed: 30844575
pii: S1549-9634(19)30041-3
doi: 10.1016/j.nano.2019.02.010
pii:
doi:

Substances chimiques

Alloys 0
titanium alloy (TiAl6V4) 12743-70-3
Titanium D1JT611TNE
Alkaline Phosphatase EC 3.1.3.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

157-168

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

Auteurs

Revathi A (R)

School of Biosciences and Technology (SBST), VIT University, Vellore, TN, India.

Mitun Das (M)

CSIR-Central Glass and Research Institute, Kolkata, WB, India; School of Mechanical Engineering (SMEC), VIT University, Vellore, TN, India.

Vamsi K Balla (VK)

CSIR-Central Glass and Research Institute, Kolkata, WB, India; School of Mechanical Engineering (SMEC), VIT University, Vellore, TN, India.

Devika D (D)

Department of Mechanical Engineering, Velammal Engineering College, Chennai, TN, India.

Dwaipayan Sen (D)

Centre for Biomaterials, Cellular and Molecular Theranostics (CBCMT), VIT University, Vellore, TN, India.

Geetha Manivasagam (G)

Centre for Biomaterials, Cellular and Molecular Theranostics (CBCMT), VIT University, Vellore, TN, India. Electronic address: geethamanivasagam@vit.ac.in.

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Classifications MeSH