Type I Secretion Systems-One Mechanism for All?


Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
03 2019
Historique:
entrez: 9 3 2019
pubmed: 9 3 2019
medline: 13 4 2019
Statut: ppublish

Résumé

Type I secretion systems (T1SS) are widespread in Gram-negative bacteria, especially in pathogenic bacteria, and they secrete adhesins, iron-scavenger proteins, lipases, proteases, or pore-forming toxins in the unfolded state in one step across two membranes without any periplasmic intermediate into the extracellular space. The substrates of T1SS are in general characterized by a C-terminal secretion sequence and nonapeptide repeats, so-called GG repeats, located N terminal to the secretion sequence. These GG repeats bind Ca

Identifiants

pubmed: 30848237
doi: 10.1128/microbiolspec.PSIB-0003-2018
doi:

Substances chimiques

Bacterial Proteins 0
Bacterial Secretion Systems 0
Type I Secretion Systems 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Olivia Spitz (O)

Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Isabelle N Erenburg (IN)

Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Tobias Beer (T)

Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Kerstin Kanonenberg (K)

Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

I Barry Holland (IB)

Institute of Genetics and Microbiology, University of Paris-Sud, Orsay, France.

Lutz Schmitt (L)

Institute of Biochemistry, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

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Classifications MeSH