Type I Secretion Systems-One Mechanism for All?
Journal
Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
entrez:
9
3
2019
pubmed:
9
3
2019
medline:
13
4
2019
Statut:
ppublish
Résumé
Type I secretion systems (T1SS) are widespread in Gram-negative bacteria, especially in pathogenic bacteria, and they secrete adhesins, iron-scavenger proteins, lipases, proteases, or pore-forming toxins in the unfolded state in one step across two membranes without any periplasmic intermediate into the extracellular space. The substrates of T1SS are in general characterized by a C-terminal secretion sequence and nonapeptide repeats, so-called GG repeats, located N terminal to the secretion sequence. These GG repeats bind Ca
Identifiants
pubmed: 30848237
doi: 10.1128/microbiolspec.PSIB-0003-2018
doi:
Substances chimiques
Bacterial Proteins
0
Bacterial Secretion Systems
0
Type I Secretion Systems
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM