No differences in microbiome changes between anti-adhesive and antibacterial ingredients in toothpastes during periodontal therapy.
dental plaque
nonsurgical periodontal therapy
periodontal microbiota
subgingival plaque
Journal
Journal of periodontal research
ISSN: 1600-0765
Titre abrégé: J Periodontal Res
Pays: United States
ID NLM: 0055107
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
31
10
2018
revised:
18
01
2019
accepted:
06
02
2019
pubmed:
10
3
2019
medline:
10
1
2020
entrez:
10
3
2019
Statut:
ppublish
Résumé
This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment either a toothpaste with anti-adhesive zinc-substituted carbonated hydroxyapatite (HA) or with antimicrobial and anti-adhesive amine fluoride/stannous fluoride (AmF/SnF Interproximal and subgingival sites harbored predominately Fusobacterium and Prevotella species associated with periodontitis, whereas buccal/lingual sites harbored mainly Streptococcus and Veillonella species associated with periodontal health. Alpha and beta diversity did not change noticeably differently between both toothpaste groups (P > 0.05, ANCOVA). Furthermore, none of the aRSVs showed a noticeably different change between the tested toothpastes during periodontal therapy (P The use of a toothpaste containing anti-adhesive HA did not induce statistically noticeably different changes on microbial composition compared to an antimicrobial and anti-adhesive AmF/SnF
Identifiants
pubmed: 30851050
doi: 10.1111/jre.12645
pmc: PMC6767489
doi:
Substances chimiques
Anti-Bacterial Agents
0
Tin Fluorides
0
Toothpastes
0
Durapatite
91D9GV0Z28
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
435-443Subventions
Organisme : Kurt Wolff GmbH, Bielefeld, Germany
Informations de copyright
© 2019 The Authors. Journal of Periodontal Research Published by John Wiley & Sons Ltd.
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