Increased infection severity in downstream cities in infectious disease transmission and tourists surveillance analysis.


Journal

Journal of theoretical biology
ISSN: 1095-8541
Titre abrégé: J Theor Biol
Pays: England
ID NLM: 0376342

Informations de publication

Date de publication:
07 06 2019
Historique:
received: 28 09 2018
revised: 28 02 2019
accepted: 04 03 2019
pubmed: 10 3 2019
medline: 10 7 2020
entrez: 10 3 2019
Statut: ppublish

Résumé

Infectious disease severely threatens human life. Human mobility and travel patterns influence the spread of infection between cities and countries. We find that the infection severity in downstream cities during outbreaks is related to transmission rate, recovery rate, travel rate, travel duration and the average number of person-to-person contacts per day. The peak value of the infected population in downstream cities is slightly higher than that in source cities. However, as the number of cities increases, the severity increase percentage during outbreaks between end and source cities is constant. The surveillance of important nodes connecting cities, such as airports and train stations, can help delay the occurrence time of infection outbreaks. The city-entry surveillance of hub cities is not only useful to these cities, but also to cities that are strongly connected (i.e., have a high travel rate) to them. The city-exit surveillance of hub cities contributes to other downstream cities, but only slightly to itself. Surveillance conducted in hub cities is highly efficient in controlling infection transmission. Only strengthening the individual immunity of frequent travellers is not efficient for infection control. However, reducing the number of person-to-person contacts per day effectively limits the spread of infection.

Identifiants

pubmed: 30851275
pii: S0022-5193(19)30097-9
doi: 10.1016/j.jtbi.2019.03.004
pmc: PMC7094123
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

20-29

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

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Auteurs

Nan Zhang (N)

Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China. Electronic address: zhangnan@hku.hk.

Pengcheng Zhao (P)

Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China.

Yuguo Li (Y)

Department of Mechanical Engineering, The University of Hong Kong, Pokfulam Road, Hong Kong, China. Electronic address: liyg@hku.hk.

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