Sialic Acids in Nonenveloped Virus Infections.
Adenovirus
Antivirals
Coxsackievirus
Polyomaviruses
Reovirus
Sialic acid
Virus structure
Viruses
Virus–glycan interactions
Journal
Advances in carbohydrate chemistry and biochemistry
ISSN: 2162-5530
Titre abrégé: Adv Carbohydr Chem Biochem
Pays: Netherlands
ID NLM: 0240537
Informations de publication
Date de publication:
2019
2019
Historique:
entrez:
11
3
2019
pubmed:
11
3
2019
medline:
5
11
2019
Statut:
ppublish
Résumé
Sialic acid-based glycoconjugates cover the surfaces of many different cell types, defining key properties of the cell surface such as overall charge or likely interaction partners. Because of this prominence, sialic acids play prominent roles in mediating attachment and entry to viruses belonging to many different families. In this review, we first describe how interactions between viruses and sialic acid-based glycan structures can be identified and characterized using a range of techniques. We then highlight interactions between sialic acids and virus capsid proteins in four different viruses, and discuss what these interactions have taught us about sialic acid engagement and opportunities to interfere with binding.
Identifiants
pubmed: 30851744
pii: S0065-2318(18)30004-0
doi: 10.1016/bs.accb.2018.09.004
pii:
doi:
Substances chimiques
Receptors, Virus
0
Sialic Acids
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
65-111Subventions
Organisme : NINDS NIH HHS
ID : P01 NS065719
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI118887
Pays : United States
Informations de copyright
© 2019 Elsevier Inc. All rights reserved.