Successes and challenges for preventing measles, mumps and rubella by vaccination.
Journal
Current opinion in virology
ISSN: 1879-6265
Titre abrégé: Curr Opin Virol
Pays: Netherlands
ID NLM: 101560941
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
19
11
2018
revised:
21
12
2018
accepted:
16
01
2019
pubmed:
11
3
2019
medline:
27
2
2020
entrez:
11
3
2019
Statut:
ppublish
Résumé
The measles, mumps and rubella (MMR) vaccine has an outstanding safety record and is highly efficacious. High coverage with MMR has led to the elimination of endemic measles, rubella, and congenital rubella syndrome in the US. The biggest challenges to global measles and rubella control and elimination are insufficient vaccination coverage globally and increasing hesitancy. Despite high two dose coverage rates, mumps has made a resurgence in the US and other countries. Mumps outbreaks have occurred primarily in close contact, high-density settings and most cases had received a second dose 10 or more years previously. Waning humoral immunity and antigenic variation of circulating wild-type mumps strains may play a role in the mumps resurgence.
Identifiants
pubmed: 30852425
pii: S1879-6257(18)30161-5
doi: 10.1016/j.coviro.2019.01.002
pii:
doi:
Substances chimiques
Antibodies, Viral
0
Measles-Mumps-Rubella Vaccine
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
110-116Informations de copyright
Copyright © 2019. Published by Elsevier B.V.