Cutaneous infection by Phaeoacremonium parasiticum.
Cutaneous infection
Feohifomicosis
Infección cutánea
Kidney transplant
Phaeohyphomycosis
Trasplante renal
Journal
Revista iberoamericana de micologia
ISSN: 2173-9188
Titre abrégé: Rev Iberoam Micol
Pays: Spain
ID NLM: 9425531
Informations de publication
Date de publication:
Historique:
received:
10
05
2018
revised:
06
08
2018
accepted:
30
10
2018
pubmed:
12
3
2019
medline:
6
2
2020
entrez:
12
3
2019
Statut:
ppublish
Résumé
Phaeoacremonium parasiticum is considered a rare infectious agent that is part of a heterogeneous group of fungi causing phaeohyphomycosis. This organism is capable of producing subcutaneous infections, eumycetomas, osteomyelitis, arthritis, myositis and also disseminated diseases, such as fungemia and endocarditis. We describe a case of cutaneous infection by P. parasiticum in a kidney transplant patient. The identification of this microorganism was performed by microbiological and histopathological studies and confirmed with the sequence of the gene encoding β-tubulin and a real time panfungal PCR targeting 18S ribosomal RNA gene. The microorganism was correctly identified by phenotypic and molecular methods. The patient was treated with oral antifungal therapy and a debulking surgery and evolved without any complication. The diagnosis of this infection is difficult and usually affects kidney transplant patients, but the reasons of this association are still unknown.
Sections du résumé
BACKGROUND
BACKGROUND
Phaeoacremonium parasiticum is considered a rare infectious agent that is part of a heterogeneous group of fungi causing phaeohyphomycosis. This organism is capable of producing subcutaneous infections, eumycetomas, osteomyelitis, arthritis, myositis and also disseminated diseases, such as fungemia and endocarditis.
CASE REPORT
METHODS
We describe a case of cutaneous infection by P. parasiticum in a kidney transplant patient. The identification of this microorganism was performed by microbiological and histopathological studies and confirmed with the sequence of the gene encoding β-tubulin and a real time panfungal PCR targeting 18S ribosomal RNA gene. The microorganism was correctly identified by phenotypic and molecular methods. The patient was treated with oral antifungal therapy and a debulking surgery and evolved without any complication.
CONCLUSIONS
CONCLUSIONS
The diagnosis of this infection is difficult and usually affects kidney transplant patients, but the reasons of this association are still unknown.
Identifiants
pubmed: 30853370
pii: S1130-1406(19)30007-5
doi: 10.1016/j.riam.2018.10.003
pii:
doi:
Substances chimiques
RNA, Ribosomal, 18S
0
Tubulin
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
90-92Informations de copyright
Copyright © 2019 Asociación Española de Micología. Publicado por Elsevier España, S.L.U. All rights reserved.