Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective.
Animals
Antigen-Presenting Cells
/ immunology
Autoimmunity
Biomarkers
Cell- and Tissue-Based Therapy
/ methods
Clinical Studies as Topic
Dendritic Cells
/ immunology
Humans
Immune Tolerance
Immunomodulation
Immunophenotyping
Immunotherapy
T-Lymphocyte Subsets
/ immunology
T-Lymphocytes, Regulatory
/ immunology
autoimmunity
cell therapy
clinic
dendritic cells
immunomonitoring
regulatory T cells
tolerance
transplantation
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2019
2019
Historique:
received:
24
10
2018
accepted:
21
01
2019
entrez:
12
3
2019
pubmed:
12
3
2019
medline:
17
1
2020
Statut:
epublish
Résumé
Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the last decade. In this perspective, we will summarize the current perspectives of the clinical application of both tolAPC and Treg, and will address future directions and the importance of immunomonitoring in clinical studies that will result in progress in the field.
Identifiants
pubmed: 30853957
doi: 10.3389/fimmu.2019.00181
pmc: PMC6395407
doi:
Substances chimiques
Biomarkers
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
181Références
Curr Opin Immunol. 2007 Jun;19(3):309-14
pubmed: 17433872
Nanomedicine (Lond). 2017 Jun;12(11):1231-1242
pubmed: 28593827
Int Immunopharmacol. 2013 Jul;16(3):358-63
pubmed: 23466550
Nat Rev Immunol. 2008 Jul;8(7):523-32
pubmed: 18566595
J Transl Med. 2016 Dec 1;14(1):332
pubmed: 27903296
Sci Rep. 2017 Sep 20;7(1):11915
pubmed: 28931834
Blood. 2011 Jan 20;117(3):1061-70
pubmed: 20952687
Eur J Immunol. 2012 Mar;42(3):771-82
pubmed: 22488365
PLoS One. 2013 Oct 24;8(10):e77729
pubmed: 24204938
Genes Immun. 2017 Sep;18(3):176-183
pubmed: 28794505
Ann Rheum Dis. 2016 Jul;75(7):1407-15
pubmed: 26324847
Nat Immunol. 2005 Dec;6(12):1219-27
pubmed: 16244650
Blood. 2002 Apr 1;99(7):2468-76
pubmed: 11895781
Nat Immunol. 2009 Sep;10(9):1000-7
pubmed: 19633673
Oncotarget. 2015 Oct 6;6(30):28621-32
pubmed: 26416420
CNS Neurosci Ther. 2015 Mar;21(3):222-30
pubmed: 25403984
Transplantation. 2016 Oct;100(10):2079-2089
pubmed: 27653226
Sci Rep. 2018 Oct 8;8(1):14985
pubmed: 30297862
Nat Rev Immunol. 2002 Feb;2(2):85-95
pubmed: 11910899
Nature. 1998 Mar 19;392(6673):245-52
pubmed: 9521319
Annu Rev Immunol. 2003;21:685-711
pubmed: 12615891
Eur J Neurol. 2011 Aug;18(8):1101-4
pubmed: 21749576
J Clin Invest. 2010 Jun;120(6):1836-47
pubmed: 20501946
Diabetes. 2012 Sep;61(9):2340-8
pubmed: 22721971
Sci Rep. 2018 May 9;8(1):7428
pubmed: 29743501
Transplant Res. 2013 Oct 25;2(1):17
pubmed: 24160259
Am J Transplant. 2016 Apr;16(4):1285-93
pubmed: 26603835
Curr Opin Immunol. 2011 Oct;23(5):679-84
pubmed: 21802270
Methods Mol Biol. 2016;1371:225-38
pubmed: 26530805
J Exp Med. 2004 May 17;199(10):1401-8
pubmed: 15148338
Hum Immunol. 2018 May;79(5):380-387
pubmed: 29448053
Diabetes Care. 2012 Sep;35(9):1817-20
pubmed: 22723342
Front Immunol. 2018 Jan 23;8:1964
pubmed: 29403473
PLoS One. 2015 Jun 03;10(6):e0127057
pubmed: 26039878
Blood. 2002 Jul 1;100(1):174-7
pubmed: 12070024
J Exp Med. 2001 Jan 15;193(2):233-8
pubmed: 11208863
Sci Transl Med. 2015 Nov 25;7(315):315ra189
pubmed: 26606968
Haematologica. 2013 Aug;98(8):1291-9
pubmed: 23242600
Front Immunol. 2015 Oct 19;6:528
pubmed: 26539195
Front Immunol. 2018 Feb 19;9:274
pubmed: 29520275
Mediators Inflamm. 2015;2015:471719
pubmed: 26819498
Mol Ther Methods Clin Dev. 2018 Jan 31;8:198-209
pubmed: 29552576
Transpl Int. 2009 Sep;22(9):884-91
pubmed: 19453998
Am J Transplant. 2017 Nov;17(11):2945-2954
pubmed: 28675676
Autoimmun Rev. 2014 Feb;13(2):138-50
pubmed: 24120737
Sci Transl Med. 2014 Apr 16;6(232):232ra51
pubmed: 24739759
J Leukoc Biol. 2008 Jul;84(1):124-33
pubmed: 18430785
J Immunol. 2005 Jun 1;174(11):7433-9
pubmed: 15905592
J Immunol. 2011 Sep 1;187(5):2072-8
pubmed: 21804023
Science. 1993 Feb 12;259(5097):974-7
pubmed: 8094901
Am J Transplant. 2017 Apr;17(4):917-930
pubmed: 27997080
J Immunol. 2014 Nov 1;193(9):4696-703
pubmed: 25252962
BioDrugs. 2013 Dec;27(6):605-14
pubmed: 23813436
Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):E2940-E2949
pubmed: 29531070
Front Immunol. 2017 Dec 22;8:1888
pubmed: 29312352
Am J Transplant. 2013 Nov;13(11):3010-20
pubmed: 24102808
FASEB J. 2003 May;17(8):836-47
pubmed: 12724343
Front Immunol. 2017 Nov 30;8:1671
pubmed: 29250066
Blood. 2014 Jul 24;124(4):638-44
pubmed: 24923299
Annu Rev Biomed Eng. 2015;17:317-49
pubmed: 26421896
Clin Immunol. 2014 Jul;153(1):23-30
pubmed: 24704576
Immunology. 2011 May;133(1):115-22
pubmed: 21342185
Am J Transplant. 2017 Apr;17(4):931-943
pubmed: 28027623
Ann Rheum Dis. 2008 Dec;67 Suppl 3:iii90-6
pubmed: 19022823
J Transl Med. 2011 Jun 09;9:89
pubmed: 21658226
Front Immunol. 2017 Dec 21;8:1870
pubmed: 29312346
Transplantation. 2015 Feb;99(2):381-4
pubmed: 25594556
Cell Mol Immunol. 2015 Jan;12(1):24-30
pubmed: 25109681
Blood. 2005 Jun 15;105(12):4743-8
pubmed: 15746082
J Clin Invest. 2012 Jan;122(1):368-82
pubmed: 22156196
PLoS One. 2011;6(10):e25857
pubmed: 22043296
BioDrugs. 2017 Aug;31(4):335-347
pubmed: 28540499
Transplant Res. 2012 Sep 28;1(1):17
pubmed: 23369628
PLoS One. 2012;7(12):e48798
pubmed: 23300516
Front Immunol. 2018 Jan 15;8:1844
pubmed: 29379498
Transplant Direct. 2015 Sep 25;1(8):e32
pubmed: 27500232
Sci Transl Med. 2015 Sep 9;7(304):304ps18
pubmed: 26355029
J Immunol. 2014 Sep 1;193(5):2600-8
pubmed: 25057005
Neurology. 2018 Mar 13;90(11):e955-e962
pubmed: 29467307
J Clin Invest. 2016 Apr 1;126(4):1413-24
pubmed: 26999600
Trends Immunol. 2002 Sep;23(9):445-9
pubmed: 12200066
Cell. 2016 Nov 3;167(4):1067-1078.e16
pubmed: 27773482
Arthritis Rheum. 2010 Dec;62(12):3656-65
pubmed: 20862679
Nat Rev Immunol. 2015 May;15(5):283-94
pubmed: 25882245
Gastroenterology. 2012 Nov;143(5):1207-1217.e2
pubmed: 22885333
Diabetes Care. 2011 Sep;34(9):2026-32
pubmed: 21680720
Discov Med. 2016 May;21(117):403-10
pubmed: 27355336
J Immunol. 2006 Nov 1;177(9):5868-77
pubmed: 17056511
Am J Transplant. 2015 Oct;15(10):2625-35
pubmed: 25988290
Nat Immunol. 2015 Nov;16(11):1153-61
pubmed: 26437244
J Immunol. 2006 Jul 15;177(2):863-8
pubmed: 16818740
Ann Rheum Dis. 2017 Jan;76(1):227-234
pubmed: 27117700
Ann Rheum Dis. 2010 Nov;69(11):2042-50
pubmed: 20551157
Transpl Int. 2008 Aug;21(8):728-41
pubmed: 18573142
Clin Immunol. 2009 Oct;133(1):22-6
pubmed: 19559653
Front Immunol. 2013 May 14;4:113
pubmed: 23717310
PLoS One. 2015 Feb 17;10(2):e0117618
pubmed: 25689405
Nature. 2014 Mar 27;507(7493):418-20
pubmed: 24670744
J Clin Invest. 2008 Nov;118(11):3619-28
pubmed: 18846251
Biol Blood Marrow Transplant. 2013 Aug;19(8):1271-3
pubmed: 23806771
Cytometry A. 2016 Jun;89(6):543-64
pubmed: 27144459
Biomed Res Int. 2016;2016:1946585
pubmed: 27725934
Autoimmun Rev. 2015 Jun;14(6):517-27
pubmed: 25633325
Haematologica. 2016 Jan;101(1):91-100
pubmed: 26471483
Immunity. 2003 May;18(5):605-17
pubmed: 12753738
J Neuroinflammation. 2016 May 20;13(1):113
pubmed: 27207486
Cell Transplant. 2011;20(11-12):1747-58
pubmed: 21457615
J Immunol. 2009 Mar 15;182(6):3556-65
pubmed: 19265134
Int Rev Immunol. 2010 Apr;29(2):156-83
pubmed: 20199240
Am J Transplant. 2013 Aug;13(8):1989-2005
pubmed: 23758811
Front Immunol. 2014 Jan 31;5:16
pubmed: 24550909
Neurol Neuroimmunol Neuroinflamm. 2018 May 18;5(4):e465
pubmed: 29845093
Am J Transplant. 2011 Jun;11(6):1236-47
pubmed: 21645255
J Leukoc Biol. 2009 Feb;85(2):243-50
pubmed: 18971286
PLoS One. 2014 Jul 29;9(7):e102390
pubmed: 25072375
Immunol Cell Biol. 2002 Oct;80(5):477-83
pubmed: 12225384
Am J Transplant. 2016 Dec;16(12):3443-3457
pubmed: 27328267
Sci Transl Med. 2013 Jun 5;5(188):188ra75
pubmed: 23740901
J Immunol. 2016 Nov 1;197(9):3607-3617
pubmed: 27683749
Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7083-7088
pubmed: 28584086
N Engl J Med. 2011 Dec 1;365(22):2055-66
pubmed: 22129252
Vaccine. 2012 Jan 5;30(2):378-87
pubmed: 22085546
Transplant Res. 2012 Sep 28;1(1):11
pubmed: 23369457
Bioinformatics. 2015 Feb 15;31(4):606-7
pubmed: 25378466
Cytotherapy. 2014 Jul;16(7):1024-30
pubmed: 24856897
Blood. 2016 Mar 24;127(12):1606-9
pubmed: 26747250
Eur J Immunol. 2007 Sep;37(9):2378-89
pubmed: 17694575
Clin Immunol. 2012 Mar;142(3):332-42
pubmed: 22225835
Front Immunol. 2015 Nov 09;6:569
pubmed: 26617604
Front Immunol. 2018 Sep 19;9:2062
pubmed: 30298066
J Crohns Colitis. 2015 Dec;9(12):1071-8
pubmed: 26303633
Am J Transplant. 2012 Dec;12(12):3449-61
pubmed: 22994804
Sci Transl Med. 2015 Jun 3;7(290):290ra87
pubmed: 26041704
Immunobiology. 2004;208(5):463-75
pubmed: 15124861
Pediatr Nephrol. 2010 Jan;25(1):61-74
pubmed: 21476231
Clin Cancer Res. 2006 Oct 1;12(19):5801-8
pubmed: 17020987
J Exp Med. 2001 Sep 17;194(6):769-79
pubmed: 11560993
J Immunother Cancer. 2016 Apr 19;4:24
pubmed: 27096100
Expert Rev Mol Diagn. 2016;16(4):387-93
pubmed: 26760313
Oncotarget. 2016 Feb 16;7(7):7563-77
pubmed: 26788992
Cytotherapy. 2015 Apr;17(4):473-86
pubmed: 25573333
Clin Exp Immunol. 2017 Feb;187(2):316-324
pubmed: 27774628
Transpl Int. 2008 Aug;21(8):742-54
pubmed: 18573141
Hum Immunol. 2009 May;70(5):353-6
pubmed: 19405174
Methods. 2018 Feb 1;134-135:164-176
pubmed: 29287915
Blood. 2010 Aug 12;116(6):935-44
pubmed: 20448110
Clin Exp Immunol. 2017 Jan;187(1):113-123
pubmed: 27667787
Nat Commun. 2018 Jul 20;9(1):2858
pubmed: 30030423
Blood. 2011 Apr 7;117(14):3921-8
pubmed: 21292771
PeerJ. 2016 Aug 30;4:e2300
pubmed: 27635311