Combined Treatment with Doxorubicin and Rapamycin Is Effective against In Vitro and In Vivo Models of Human Glioblastoma.
chemotherapy
doxorubicin
glioblastoma
mTOR inhibitor
rapamycin
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
09 Mar 2019
09 Mar 2019
Historique:
received:
11
02
2019
revised:
05
03
2019
accepted:
06
03
2019
entrez:
13
3
2019
pubmed:
13
3
2019
medline:
13
3
2019
Statut:
epublish
Résumé
Despite numerous clinical trials, glioblastoma (GBM) remains a tumor that is difficult to treat. The aim of this study was to investigate the potential of a new pharmacological approach, combining doxorubicin (Dox) and rapamycin (Rapa), in in vitro and in vivo GBM models. Cytotoxic and anti-proliferative effects of Rapa
Identifiants
pubmed: 30857276
pii: jcm8030331
doi: 10.3390/jcm8030331
pmc: PMC6462908
pii:
doi:
Types de publication
Journal Article
Langues
eng
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