Killer immunoglobulin like receptor gene profiling in Western Indian population.


Journal

Human immunology
ISSN: 1879-1166
Titre abrégé: Hum Immunol
Pays: United States
ID NLM: 8010936

Informations de publication

Date de publication:
Jul 2019
Historique:
received: 26 02 2019
revised: 07 03 2019
accepted: 07 03 2019
pubmed: 13 3 2019
medline: 18 12 2019
entrez: 13 3 2019
Statut: ppublish

Résumé

One hundred and sixty one healthy unrelated hematopoietic stem cell transplant donors from Western Indian were enrolled in this study. The study was initiated to observe the genotypic diversity of 16 killer immunoglobulin like receptor (KIR) genes in this population. KIR genotyping was carried out using the PCR-SSP technique. 56 KIR genotypes were observed in our population, where 15 genotypes were reported for the first time in any population. The KIR genotype data for the population can be accessed from Allele Frequencies Net Database under the population name "India Western KIR" and identifier "3570".

Identifiants

pubmed: 30858076
pii: S0198-8859(19)30206-X
doi: 10.1016/j.humimm.2019.03.010
pii:
doi:

Substances chimiques

Receptors, KIR 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

427-428

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

Auteurs

Selma Zenia D'Silva (SZ)

HLA & Immunogenetics Laboratory, Department of Transfusion Medicine, Tata Memorial Hospital, Parel, Mumbai 400012, India.

Sandeep Kumar Dhanda (SK)

Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.

Meenakshi Singh (M)

HLA & Immunogenetics Laboratory, Department of Transfusion Medicine, Tata Memorial Hospital, Parel, Mumbai 400012, India. Electronic address: meenakshisingha@gmail.com.

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Classifications MeSH