The genome of the jellyfish Clytia hemisphaerica and the evolution of the cnidarian life-cycle.

Animals Evolution, Molecular Genome Hydrozoa

Journal

Nature ecology & evolution

ISSN: 2397-334X

Titre abrégé: Nat Ecol Evol

Pays: England

ID NLM: 101698577

Informations de publication

Date de publication:
05 2019

Historique:

received: 17 07 2018

accepted: 30 01 2019

pubmed: 13 3 2019

medline: 12 10 2019

entrez: 13 3 2019

Statut: ppublish

Résumé

Jellyfish (medusae) are a distinctive life-cycle stage of medusozoan cnidarians. They are major marine predators, with integrated neurosensory, muscular and organ systems. The genetic foundations of this complex form are largely unknown. We report the draft genome of the hydrozoan jellyfish Clytia hemisphaerica and use multiple transcriptomes to determine gene use across life-cycle stages. Medusa, planula larva and polyp are each characterized by distinct transcriptome signatures reflecting abrupt life-cycle transitions and all deploy a mixture of phylogenetically old and new genes. Medusa-specific transcription factors, including many with bilaterian orthologues, associate with diverse neurosensory structures. Compared to Clytia, the polyp-only hydrozoan Hydra has lost many of the medusa-expressed transcription factors, despite similar overall rates of gene content evolution and sequence evolution. Absence of expression and gene loss among Clytia orthologues of genes patterning the anthozoan aboral pole, secondary axis and endomesoderm support simplification of planulae and polyps in Hydrozoa, including loss of bilateral symmetry. Consequently, although the polyp and planula are generally considered the ancestral cnidarian forms, in Clytia the medusa maximally deploys the ancestral cnidarian-bilaterian transcription factor gene complement.

Identifiants

DOI: 10.1038/s41559-019-0833-2 PMID: 30858591

pubmed: 30858591

doi: 10.1038/s41559-019-0833-2

pii: 10.1038/s41559-019-0833-2

doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

Pagination

801-810

Commentaires et corrections

Type : CommentIn

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