Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration.

Cerebrovascular disease Dementia Magnetic resonance imaging Radiology Stroke

Journal

Alzheimer's & dementia (Amsterdam, Netherlands)
ISSN: 2352-8729
Titre abrégé: Alzheimers Dement (Amst)
Pays: United States
ID NLM: 101654604

Informations de publication

Date de publication:
Dec 2019
Historique:
entrez: 13 3 2019
pubmed: 13 3 2019
medline: 13 3 2019
Statut: epublish

Résumé

Many consequences of cerebrovascular disease are identifiable by magnetic resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of data. The European Union Joint Program on Neurodegenerative Diseases (EU JPND) funded the HARmoNizing Brain Imaging MEthodS for VaScular Contributions to Neurodegeneration (HARNESS) initiative, with a focus on cerebral small vessel disease. Surveys, teleconferences, and an in-person workshop were used to identify gaps in knowledge and to develop tools for harmonizing imaging and analysis. A framework for neuroimaging biomarker development was developed based on validating repeatability and reproducibility, biological principles, and feasibility of implementation. The status of current MRI biomarkers was reviewed. A website was created at www.harness-neuroimaging.org with acquisition protocols, a software database, rating scales and case report forms, and a deidentified MRI repository. The HARNESS initiative provides resources to reduce variability in measurement in MRI studies of cerebral small vessel disease.

Identifiants

pubmed: 30859119
doi: 10.1016/j.dadm.2019.01.002
pii: S2352-8729(19)30004-1
pmc: PMC6396326
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

191-204

Subventions

Organisme : NINDS NIH HHS
ID : UH3 NS100605
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG054076
Pays : United States
Organisme : NIA NIH HHS
ID : RF1 AG059421
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG049607
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG008122
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG052409
Pays : United States
Organisme : NIA NIH HHS
ID : P30 AG010129
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG049505
Pays : United States
Organisme : Medical Research Council
ID : MR/J006971/1
Pays : United Kingdom
Organisme : NINDS NIH HHS
ID : R01 NS017950
Pays : United States

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Auteurs

Eric E Smith (EE)

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.

Geert Jan Biessels (GJ)

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

François De Guio (F)

Department of Neurology, Lariboisière Hospital, University Paris Diderot, Paris, France.

Frank Erik de Leeuw (FE)

Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Donders Center for Medical Neuroscience, Radboud University Medical Center, Nijmegen, Netherlands.

Simon Duchesne (S)

CERVO Research Center, Quebec Mental Health Institute, Québec, Canada.
Radiology Department, Université Laval, Québec, Canada.

Marco Düring (M)

Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-Universität LMU, Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Richard Frayne (R)

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.
Seaman Family MR Centre, Foothills Medical Centre, Calgary, Alberta, Canada.

M Arfan Ikram (MA)

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.

Eric Jouvent (E)

Department of Neurology, Lariboisière Hospital, University Paris Diderot, Paris, France.

Bradley J MacIntosh (BJ)

Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Department of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.

Michael J Thrippleton (MJ)

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.
UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.

Meike W Vernooij (MW)

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Hieab Adams (H)

Department of Epidemiology, Erasmus University Medical Center, Rotterdam, Netherlands.
Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Walter H Backes (WH)

Department of Radiology & Nuclear Medicine, School for Mental Health & Neuroscience, Maastricht University Medical Center, Maastricht, The Netherlands.

Lucia Ballerini (L)

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.
UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.

Sandra E Black (SE)

Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.
Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, Ontario, Canada.
Department of Medicine (Neurology), Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

Christopher Chen (C)

Memory Aging and Cognition Centre, Department of Pharmacology, National University of Singapore, Singapore.

Rod Corriveau (R)

National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.

Charles DeCarli (C)

Department of Neurology and Center for Neuroscience, University of California at Davis, Davis, CA, USA.

Steven M Greenberg (SM)

J. Philip Kistler Stroke Research Center, Stroke Service and Memory Disorders Unit, Massachusetts General Hospital, Boston, MA, USA.

M Edip Gurol (ME)

J. Philip Kistler Stroke Research Center, Stroke Service and Memory Disorders Unit, Massachusetts General Hospital, Boston, MA, USA.

Michael Ingrisch (M)

Department of Radiology, Ludwig-Maximilians-University Hospital Munich, Munich, Germany.

Dominic Job (D)

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.
UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.

Bonnie Y K Lam (BYK)

Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

Lenore J Launer (LJ)

National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.

Jennifer Linn (J)

Institute of Neuroradiology, University Hospital Carl Gustav Carus, Dresden, Germany.

Cheryl R McCreary (CR)

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Seaman Family MR Centre, Foothills Medical Centre, Calgary, Alberta, Canada.

Vincent C T Mok (VCT)

Therese Pei Fong Chow Research Centre for Prevention of Dementia, Gerald Choa Neuroscience Centre, Lui Che Woo Institute of Innovative Medicine, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong.

Leonardo Pantoni (L)

Luigi Sacco Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.

G Bruce Pike (GB)

Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada.
Department of Radiology, University of Calgary, Calgary, Alberta, Canada.
Hotchkiss Brain Institute, University of Calgary, Alberta, Canada.

Joel Ramirez (J)

Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Department of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.
Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.

Yael D Reijmer (YD)

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands.

Jose Rafael Romero (JR)

Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
Framingham Heart Study, Framingham, MA, USA.

Stefan Ropele (S)

Department of Neurology, Medical University of Graz, Graz, Austria.

Natalia S Rost (NS)

J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Boston, MA, USA.

Perminder S Sachdev (PS)

Centre for Healthy Brain Ageing, University of New South Wales, Sydney, Australia.

Christopher J M Scott (CJM)

Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Department of Medical Biophysics, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.
Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, University of Toronto, Toronto, Ontario, Canada.

Sudha Seshadri (S)

Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, TX, USA.

Mukul Sharma (M)

Population Health Research Institute, Hamilton, Ontario, Canada.
Department of Medicine (Neurology) McMaster University, Hamilton, Ontario, Canada.

Steven Sourbron (S)

Imaging Biomarkers Group, Department of Biomedical Imaging Sciences, University of Leeds, Leeds, UK.

Rebecca M E Steketee (RME)

Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.

Richard H Swartz (RH)

Department of Medicine (Neurology), University of Toronto, Toronto, Canada.
Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Canada.

Robert van Oostenbrugge (R)

Department of Neurology, School for Mental Health and Neuroscience, Maastricht University Medical Center, Maastricht, the Netherlands.

Matthias van Osch (M)

C.J. Gorter Center for high field MRI, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Sanneke van Rooden (S)

Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Anand Viswanathan (A)

J. Philip Kistler Stroke Research Center, Stroke Service and Memory Disorders Unit, Massachusetts General Hospital, Boston, MA, USA.

David Werring (D)

University College London Queen Square institute of Neurology, London, UK.

Martin Dichgans (M)

Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig-Maximilians-Universität LMU, Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Joanna M Wardlaw (JM)

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
Edinburgh Imaging, University of Edinburgh, Edinburgh, UK.
UK Dementia Research Institute, University of Edinburgh, Edinburgh, UK.

Classifications MeSH