Human parthenogenetic neural stem cell grafts promote multiple regenerative processes in a traumatic brain injury model.


Journal

Theranostics
ISSN: 1838-7640
Titre abrégé: Theranostics
Pays: Australia
ID NLM: 101552395

Informations de publication

Date de publication:
2019
Historique:
received: 11 09 2018
accepted: 16 11 2018
entrez: 15 3 2019
pubmed: 15 3 2019
medline: 16 1 2020
Statut: epublish

Résumé

International Stem Cell Corporation human parthenogenetic neural stem cells (ISC-hpNSC) have potential therapeutic value for patients suffering from traumatic brain injury (TBI). Here, we demonstrate the behavioral and histological effects of transplanting ISC-hpNSC intracerebrally in an animal model of TBI.

Identifiants

pubmed: 30867814
doi: 10.7150/thno.29868
pii: thnov09p1029
pmc: PMC6401413
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1029-1046

Déclaration de conflit d'intérêts

Competing Interests: A.S., I.G., R.G., and R.K. are employees and stock holders of International Stem Cell Corporation. C.V.B. received funding from International Stem Cell Corporation for this study.

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Auteurs

Jea-Young Lee (JY)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Sandra Acosta (S)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Julian P Tuazon (JP)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Kaya Xu (K)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Hung Nguyen (H)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Trenton Lippert (T)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Michael G Liska (MG)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

Andrey Semechkin (A)

International Stem Cell Corporation, Carlsbad, CA.

Ibon Garitaonandia (I)

International Stem Cell Corporation, Carlsbad, CA.

Rodolfo Gonzalez (R)

International Stem Cell Corporation, Carlsbad, CA.

Russell Kern (R)

International Stem Cell Corporation, Carlsbad, CA.
Cyto Therapeutics, Melbourne, Australia.

Cesario V Borlongan (CV)

Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, USF Morsani College of Medicine, Tampa, FL.

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Classifications MeSH