A Rare Case of Gastrointestinal Stromal Tumor with a Liver Metastasis Infiltrating the Inferior Vena Cava and Extending to the Right Atrium with an Early Recurrence after Surgical Extraction.
Journal
Case reports in cardiology
ISSN: 2090-6404
Titre abrégé: Case Rep Cardiol
Pays: United States
ID NLM: 101576452
Informations de publication
Date de publication:
2019
2019
Historique:
received:
01
07
2018
revised:
20
12
2018
accepted:
08
01
2019
entrez:
15
3
2019
pubmed:
15
3
2019
medline:
15
3
2019
Statut:
epublish
Résumé
Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract. The major cause of GIST is the presence of an abnormal form of tyrosine protein kinase (KIT) protein also known as CD117, which causes uncontrollable growth of the gastrointestinal cells. Most studies report incidences between 10 and 15 cases of GISTs per million. Metastases to the liver and peritoneum are the most frequent. We report a case of advanced GIST with a liver metastasis infiltrating the inferior vena cava (IVC) and extending to the right atrium in the form of a large, floating, isolated intracardiac liver metastasis with diastolic prolapsing through the tricuspid valve. This is a very rare manifestation. One week after heart surgery and removal of a 5 × 6 cm tumor mass from the right atrium and the IVC, echocardiography depicted an early recurrence.
Identifiants
pubmed: 30867967
doi: 10.1155/2019/2623403
pmc: PMC6379877
doi:
Types de publication
Case Reports
Langues
eng
Pagination
2623403Références
Science. 2003 Jan 31;299(5607):708-10
pubmed: 12522257
BMC Cancer. 2004 Oct 09;4:74
pubmed: 15473910
J Clin Pathol. 2007 Jan;60(1):27-34
pubmed: 17098886
Semin Diagn Pathol. 2006 May;23(2):70-83
pubmed: 17193820
Bosn J Basic Med Sci. 2007 May;7(2):176-9
pubmed: 17489757
Hum Pathol. 2008 Oct;39(10):1411-9
pubmed: 18774375
Lancet. 2009 Mar 28;373(9669):1097-104
pubmed: 19303137
Lancet Oncol. 2009 Nov;10(11):1045-52
pubmed: 19793678
Rare Tumors. 2010 Dec 31;2(4):e58
pubmed: 21234250
Indian J Pathol Microbiol. 2011 Apr-Jun;54(2):362-4
pubmed: 21623091
Curr Cardiovasc Imaging Rep. 2014;7:9281
pubmed: 25018846
J Clin Oncol. 2016 Jan 20;34(3):244-50
pubmed: 26527782
Cancer Epidemiol. 2016 Feb;40:39-46
pubmed: 26618334
J Cancer Res Ther. 2017 Oct-Dec;13(6):889-900
pubmed: 29237949
Science. 1998 Jan 23;279(5350):577-80
pubmed: 9438854