Bacteriophages Isolated in China for the Control of Pectobacterium carotovorum Causing Potato Soft Rot in Kenya.


Journal

Virologica Sinica
ISSN: 1995-820X
Titre abrégé: Virol Sin
Pays: Netherlands
ID NLM: 101514185

Informations de publication

Date de publication:
Jun 2019
Historique:
received: 03 08 2018
accepted: 10 12 2018
pubmed: 15 3 2019
medline: 14 8 2019
entrez: 15 3 2019
Statut: ppublish

Résumé

Soft rot is an economically significant disease in potato and one of the major threats to sustainable potato production. This study aimed at isolating lytic bacteriophages and evaluating methods for and the efficacy of applying phages to control potato soft rot caused by Pectobacterium carotovorum. Eleven bacteriophages isolated from soil and water samples collected in Wuhan, China, were used to infect P. carotovorum host strains isolated from potato tubers showing soft rot symptoms in Nakuru county, Kenya. The efficacy of the phages in controlling soft rot disease was evaluated by applying individual phage strains or a phage cocktail on potato slices and tubers at different time points before or after inoculation with a P. carotovorum strain. The phages could lyse 20 strains of P. carotovorum, but not Pseudomonas fluorescens control strains. Among the 11 phages, Pectobacterium phage Wc5r, interestingly showed cross-activity against Pectobacterium atrosepticum and two phage-resistant P. carotovorum strains. Potato slice assays showed that the phage concentration and timing of application are crucial factors for effective soft rot control. Phage cocktail applied at a concentration of 1 × 10

Identifiants

pubmed: 30868359
doi: 10.1007/s12250-019-00091-7
pii: 10.1007/s12250-019-00091-7
pmc: PMC6599505
doi:

Substances chimiques

Biological Control Agents 0

Types de publication

Journal Article

Langues

eng

Pagination

287-294

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Auteurs

Peter Muturi (P)

Key Laboratory of Emerging Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.
University of Chinese Academy of Sciences, Beijing, 100049, China.

Junping Yu (J)

Key Laboratory of Emerging Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China.

Alice Nyambura Maina (AN)

School of Biological and Life Sciences, Technical University of Kenya, Nairobi, 00200, Kenya.
School of Biological Sciences, University of Nairobi, Nairobi, 00100, Kenya.

Samuel Kariuki (S)

Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, 00202, Kenya.

Francis B Mwaura (FB)

School of Biological Sciences, University of Nairobi, Nairobi, 00100, Kenya.

Hongping Wei (H)

Key Laboratory of Emerging Pathogens and Biosafety, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China. hpwei@wh.iov.cn.
Sino-Africa Joint Research Centre, Nairobi, 00200, Kenya. hpwei@wh.iov.cn.

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Classifications MeSH