An Overview of the Polymorphisms of Circadian Genes Associated With Endocrine Cancer.
breast cancer
circadian clock genes
endocrine cancer
ovarian cancer
pancreatic cancer
polymorphism
prostate cancer
thyroid cancer
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2019
2019
Historique:
received:
30
09
2018
accepted:
04
02
2019
entrez:
16
3
2019
pubmed:
16
3
2019
medline:
16
3
2019
Statut:
epublish
Résumé
A major consequence of the world industrialized lifestyle is the increasing period of unnatural light in environments during the day and artificial lighting at night. This major change disrupts endogenous homeostasis with external circadian cues, which has been associated to higher risk of diseases affecting human health, mainly cancer among others. Circadian disruption promotes tumor development and accelerate its fast progression. The dysregulation mechanisms of circadian genes is greatly affected by the genetic variability of these genes. To date, several core circadian genes, also called circadian clock genes, have been identified, comprising the following:
Identifiants
pubmed: 30873119
doi: 10.3389/fendo.2019.00104
pmc: PMC6401647
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
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