Burn CAG titer Candida Mortality

Journal

World journal of plastic surgery
ISSN: 2228-7914
Titre abrégé: World J Plast Surg
Pays: Iran
ID NLM: 101639130

Informations de publication

Date de publication:
Jan 2019
Historique:
entrez: 16 3 2019
pubmed: 16 3 2019
medline: 16 3 2019
Statut: ppublish

Résumé

Mortality in burn patients has several contributing factors as sex, age, degree of burns, or inhalation injuries. Usefulness of From 1988 to 2011, 877 burn intensive care patients were evaluated for age, sex, total burn surface area (TBSA), multi organ failure (MOF), burn depth, escharotomy, fasciotomy, antibiotic use, co-morbidities, CAG titer and intubation. From 870 admitted patients, 190 patients were not enrolled. Increasing age was correlated with a higher mortality. The abbreviated burn severity index (ABSI) score of the deceased was 4 points and the TBSA was 20% higher than the survivors. The correlation for age, intubation, TBSA, inhalation injury, MOF, CAG titer, antibiotic use and escharotomy was significant. An increasing mortality was noted with antibiotic use and a CAG titer of 1:8 and higher. CAG titer of 1:8 and higher had a sensitivity of 51.1% and specificity of 86.3% for mortality. Multivariate analysis confirmed high influence of older age, MOF, comorbidities, antibiotic use and CAG titer of 1:8 and higher on mortality. There was a significant correlation for sex, younger age and CAG titer. CAG titers of 1:8 and higher might warrant beginning of antimycotic treatment in elderly patients with high TBSA to avoid increase in mortality.

Sections du résumé

BACKGROUND BACKGROUND
Mortality in burn patients has several contributing factors as sex, age, degree of burns, or inhalation injuries. Usefulness of
METHODS METHODS
From 1988 to 2011, 877 burn intensive care patients were evaluated for age, sex, total burn surface area (TBSA), multi organ failure (MOF), burn depth, escharotomy, fasciotomy, antibiotic use, co-morbidities, CAG titer and intubation.
RESULTS RESULTS
From 870 admitted patients, 190 patients were not enrolled. Increasing age was correlated with a higher mortality. The abbreviated burn severity index (ABSI) score of the deceased was 4 points and the TBSA was 20% higher than the survivors. The correlation for age, intubation, TBSA, inhalation injury, MOF, CAG titer, antibiotic use and escharotomy was significant. An increasing mortality was noted with antibiotic use and a CAG titer of 1:8 and higher. CAG titer of 1:8 and higher had a sensitivity of 51.1% and specificity of 86.3% for mortality. Multivariate analysis confirmed high influence of older age, MOF, comorbidities, antibiotic use and CAG titer of 1:8 and higher on mortality. There was a significant correlation for sex, younger age and CAG titer.
CONCLUSION CONCLUSIONS
CAG titers of 1:8 and higher might warrant beginning of antimycotic treatment in elderly patients with high TBSA to avoid increase in mortality.

Identifiants

pubmed: 30873358
doi: 10.29252/wjps.8.1.18.
pmc: PMC6409138
doi:

Types de publication

Journal Article

Langues

eng

Pagination

18-24

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Sebastian Jachec (S)

Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Burns, University Hospital Cologne, Merheim, Germany.

Walter Perbix (W)

Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Burns, University Hospital Cologne, Merheim, Germany.

Perbix Fuchs (P)

Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Burns, University Hospital Cologne, Merheim, Germany.

Rolf Lefering (R)

Institute for Research in Operative Medicine (IFOM), University Hospital Cologne, Merheim, Germany.

Christian Weinand (C)

Department of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Burns, University Hospital Cologne, Merheim, Germany.
Department of Plastic and Aesthetic Surgery, Hand Surgery, Burns Helios Hospital Gifhorn, University of Magdeburg, Germany.

Classifications MeSH