Environmentally-induced epigenetic conversion of a piRNA cluster.

D. melanogaster epigenetics genetics genomics germline heterochromatin non coding small RNA temperature transposable element

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
15 03 2019
Historique:
received: 04 07 2018
accepted: 06 03 2019
entrez: 16 3 2019
pubmed: 16 3 2019
medline: 31 3 2020
Statut: epublish

Résumé

Transposable element (TE) activity is repressed in animal gonads by PIWI-interacting RNAs (piRNAs) produced by piRNA clusters. Current models in flies propose that germinal piRNA clusters are functionally defined by the maternal inheritance of piRNAs produced during the previous generation. Taking advantage of an inactive, but ready to go, cluster of This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (see decision letter).

Identifiants

pubmed: 30875295
doi: 10.7554/eLife.39842
pii: 39842
pmc: PMC6420265
doi:
pii:

Substances chimiques

RNA, Small Interfering 0

Banques de données

GEO
['GSE116122']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Fondation ARC pour la Recherche sur le Cancer
ID : SFI20131200470
Pays : International
Organisme : Fondation pour la Recherche Médicale
ID : DEP20131128532
Pays : International
Organisme : Agence Nationale de la Recherche
ID : plastisipi
Pays : International
Organisme : Pierre and Marie Curie University
ID : EME1223
Pays : International

Informations de copyright

© 2019, Casier et al.

Déclaration de conflit d'intérêts

KC, VD, NG, CH, EV, CV, SR, EB, LT, AB No competing interests declared

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Auteurs

Karine Casier (K)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Valérie Delmarre (V)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Nathalie Gueguen (N)

GReD, Université Clermont Auvergne, CNRS, INSERM, BP 10448, Clermont-Ferrand, France.

Catherine Hermant (C)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Elise Viodé (E)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Chantal Vaury (C)

GReD, Université Clermont Auvergne, CNRS, INSERM, BP 10448, Clermont-Ferrand, France.

Stéphane Ronsseray (S)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Emilie Brasset (E)

GReD, Université Clermont Auvergne, CNRS, INSERM, BP 10448, Clermont-Ferrand, France.

Laure Teysset (L)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

Antoine Boivin (A)

Laboratoire Biologie du Développement, UMR7622, Sorbonne Université, CNRS, Institut de Biologie Paris-Seine, Paris, France.

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