Conjugate Eye Deviation in Unilateral Lateral Medullary Infarction.

cerebral stroke dorsolateral medullary syndrome eye motility disorders neurological examination orthoptics transient ischemic attack

Journal

Journal of clinical neurology (Seoul, Korea)
ISSN: 1738-6586
Titre abrégé: J Clin Neurol
Pays: Korea (South)
ID NLM: 101252374

Informations de publication

Date de publication:
Apr 2019
Historique:
received: 10 10 2018
revised: 02 12 2018
accepted: 03 12 2018
pubmed: 17 3 2019
medline: 17 3 2019
entrez: 17 3 2019
Statut: ppublish

Résumé

The initial diagnosis of medullary infarction can be challenging since CT and even MRI results in the very acute phase are often negative. A retrospective, observer-blinded study of horizontal conjugate eye deviation was performed in 1) 50 consecutive patients [age 58±15 years (mean±SD), 74% male, National Institutes of Health Stroke Scale 2±1] with acute unilateral lateral medullary infarction as seen in MRI (infarction group), 2) 54 patients with transient brainstem symptoms [transient ischemic attack of brainstem (TIA) group; age 69±16 years, 59% male], and 3) 53 patients (age 59±20 years, 49% male) with diagnoses other than stroke (control group). Conjugate eye deviation was found in all patients in the infarction group [ All patients with MRI-demonstrated unilateral medullary infarction showed conjugate eye deviation. Therefore, conjugate eye deviation in patients with suspected acute lateral medullary infarction is a helpful sensitive sign for supporting the diagnosis, particularly if the deviation is >20°.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
The initial diagnosis of medullary infarction can be challenging since CT and even MRI results in the very acute phase are often negative.
METHODS METHODS
A retrospective, observer-blinded study of horizontal conjugate eye deviation was performed in 1) 50 consecutive patients [age 58±15 years (mean±SD), 74% male, National Institutes of Health Stroke Scale 2±1] with acute unilateral lateral medullary infarction as seen in MRI (infarction group), 2) 54 patients with transient brainstem symptoms [transient ischemic attack of brainstem (TIA) group; age 69±16 years, 59% male], and 3) 53 patients (age 59±20 years, 49% male) with diagnoses other than stroke (control group).
RESULTS RESULTS
Conjugate eye deviation was found in all patients in the infarction group [
CONCLUSIONS CONCLUSIONS
All patients with MRI-demonstrated unilateral medullary infarction showed conjugate eye deviation. Therefore, conjugate eye deviation in patients with suspected acute lateral medullary infarction is a helpful sensitive sign for supporting the diagnosis, particularly if the deviation is >20°.

Identifiants

pubmed: 30877695
doi: 10.3988/jcn.2019.15.2.228
pii: 15.e9
pmc: PMC6444143
doi:

Types de publication

Journal Article

Langues

eng

Pagination

228-234

Informations de copyright

Copyright © 2019 Korean Neurological Association.

Déclaration de conflit d'intérêts

The authors have no financial conflicts of interest.

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Auteurs

Julian Teufel (J)

Department of Neurology, Ludwig Maximilian University (LMU), Munich, Germany.
German Center for Vertigo and Balance Disorders, Ludwig Maximilian University (LMU), Munich, Germany.

Michael Strupp (M)

Department of Neurology, Ludwig Maximilian University (LMU), Munich, Germany.
German Center for Vertigo and Balance Disorders, Ludwig Maximilian University (LMU), Munich, Germany.

Jennifer Linn (J)

Department of Neuroradiology, University Hospital Carl Gustav Carus, Dresden, Germany.

Roger Kalla (R)

Department of Neurology Inselspital, Bern University Hospital, Bern, Switzerland.

Katharina Feil (K)

Department of Neurology, Ludwig Maximilian University (LMU), Munich, Germany.
German Center for Vertigo and Balance Disorders, Ludwig Maximilian University (LMU), Munich, Germany. katharina.feil@med.uni-muenchen.de.

Classifications MeSH