Childhood trauma and adolescent psychotic experiences in a community-based cohort: The potential role of positive attributes as a protective factor.


Journal

Schizophrenia research
ISSN: 1573-2509
Titre abrégé: Schizophr Res
Pays: Netherlands
ID NLM: 8804207

Informations de publication

Date de publication:
03 2019
Historique:
received: 23 02 2018
revised: 11 06 2018
accepted: 14 06 2018
entrez: 19 3 2019
pubmed: 19 3 2019
medline: 30 4 2020
Statut: ppublish

Résumé

To investigate how a set of positive social and personality characteristics called 'positive attributes' affects the emergence and persistence of Psychotic Experiences (PE) in adolescence. We used data from a community-based Brazilian High-Risk Cohort (HRC). 2511 6-12 year-old children were evaluated at baseline, and 80.05% completed a 3-year follow-up interview. At baseline, childhood trauma was assessed using parent- and self-report, and positive attributes were assessed by parent-report. Trained psychologists rated self-reported PE at both time points. Linear models evaluated the effect of childhood trauma and positive attributes on PE at follow-up. Mediation models tested i.) the indirect effect of positive attributes on the association between childhood trauma and follow-up PE and, ii.) the indirect effect of childhood trauma and positive attributes on the relationship between PE at baseline and follow-up. Higher levels of baseline PE (B = 0.157, p < .001) and higher childhood trauma (B = 0.110, p < .001) were associated with increased follow-up PE. Higher positive attributes predicted lower PE after 3 years, adjusting for the prevalence of baseline PE and childhood trauma (B = -0.042, p < .022). Positive attributes partially mediated the relationship between childhood trauma and follow-up PE. The indirect pathway of childhood trauma and positive attributes mediated the association between baseline and follow-up PE. Higher levels of positive social and behavioral traits in childhood may diminish the subsequent emergence of PE. As these attributes can be promoted, our findings suggest that positive attributes may represent a novel target for preventive interventions in children at risk of developing PE.

Identifiants

pubmed: 30879477
pii: S0920-9964(18)30382-7
doi: 10.1016/j.schres.2018.06.044
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

23-29

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Pedro M Pan (PM)

Department of Psychiatry, Laboratório Interdisciplinar de Neurociências Clínicas (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil; National Institute of Developmental Psychiatry, São Paulo, Brazil. Electronic address: pedro.pan@unifesp.br.

Ary Gadelha (A)

Department of Psychiatry, Laboratório Interdisciplinar de Neurociências Clínicas (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil; National Institute of Developmental Psychiatry, São Paulo, Brazil.

Felipe C Argolo (FC)

Department of Psychiatry, Laboratório Interdisciplinar de Neurociências Clínicas (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil.

Mauricio S Hoffmann (MS)

National Institute of Developmental Psychiatry, São Paulo, Brazil; Departament of Neuropsychiatry, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.

Felipe B Arcadepani (FB)

Department of Psychiatry, Laboratório Interdisciplinar de Neurociências Clínicas (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil.

Euripedes C Miguel (EC)

National Institute of Developmental Psychiatry, São Paulo, Brazil; Department & Institute of Psychiatry, Universidade de São Paulo, São Paulo, Brazil.

Luis A Rohde (LA)

National Institute of Developmental Psychiatry, São Paulo, Brazil; Department of Psychiatry, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Philip McGuire (P)

Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

Giovanni A Salum (GA)

National Institute of Developmental Psychiatry, São Paulo, Brazil; Department of Psychiatry, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Rodrigo A Bressan (RA)

Department of Psychiatry, Laboratório Interdisciplinar de Neurociências Clínicas (LiNC), Universidade Federal de São Paulo, São Paulo, Brazil; National Institute of Developmental Psychiatry, São Paulo, Brazil; Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.

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