Retrospective study identified fish and milk as the main culprits in cases of food protein-induced enterocolitis syndrome.
Fish allergy
Food allergies
Food protein-induced enterocolitis syndrome
Immunoglobulin E
Milk allergy
Journal
Acta paediatrica (Oslo, Norway : 1992)
ISSN: 1651-2227
Titre abrégé: Acta Paediatr
Pays: Norway
ID NLM: 9205968
Informations de publication
Date de publication:
10 2019
10 2019
Historique:
received:
20
01
2019
revised:
06
03
2019
accepted:
12
03
2019
pubmed:
19
3
2019
medline:
2
10
2020
entrez:
19
3
2019
Statut:
ppublish
Résumé
Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E (IgE)-mediated food allergy, which is confined to the gastrointestinal tract and occurs most frequently in the first year of life. Our aim was to examine the clinical features, causative agents and outcomes of Greek children with FPIES. This was a five-year (2013-2017) retrospective study, based on chart reviews of 78 children with FPIES from six Greek paediatric allergy centres. Only five children needed an oral food challenge (OFC) for diagnosis, but 54 children (69%) had OFCs to monitor tolerance development. The most common problems were fish and milk, which affected affecting 42 (54%) and 25 (35%) of children, respectively. The median age of tolerance based on the results of the negative OFCs occurred by 34.0 (26.6-58.4) months. Fish and milk were tolerated by 24 (57%) and 13 (52%) of children by 43.8 and 24.3 months, respectively. Coexisting IgE sensitisation to the offending food was related to delayed tolerance. Fish and milk were the most common food allergies in our series of Greek children with FPIES. Cases with IgE sensitisation to the food trigger took longer to resolve their allergies.
Substances chimiques
Fish Proteins, Dietary
0
Milk Proteins
0
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
1901-1904Informations de copyright
©2019 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.
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