Depression and aging with HIV: Associations with health-related quality of life and positive psychological factors.
Journal
Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073
Informations de publication
Date de publication:
15 05 2019
15 05 2019
Historique:
received:
25
09
2018
revised:
31
12
2018
accepted:
04
03
2019
pubmed:
19
3
2019
medline:
13
7
2019
entrez:
19
3
2019
Statut:
ppublish
Résumé
Depression is prevalent among persons living with HIV (PLWH). This study investigated the relationships between depressive symptomatology, health-related quality of life (HRQoL), and positive psychological factors in PLWH and age-matched HIV-individuals. One hundred twenty-two PLWH and 94 HIV- individuals, recruited in three age cohorts (36-45, 46-55, 56-65 years old), completed self-report questionnaires on depressive symptoms (CES-D), HRQoL, and positive psychological factors (resilience, grit, and self-rated successful aging [SRSA]). Participants were classified based on HIV status (H+ vs H-) and elevated depressive symptoms (D+ vs D-) into four groups (H+/D+; H-/D+; H+/D-; H-/D-). Fifty-eight percent of PLWH had elevated depressive scores, compared to 33% of HIV- individuals (p < 0.001). The proportion of individuals reporting elevated depressive symptoms only differed among individuals 36-45 years old (H+: 61.5%; H-: 17.9%; p < 0.001). Individuals in the H+/D+ group reported the lowest HRQoL, resilience, grit, and SRSA across age cohorts. However, there were no differences on HRQoL or positive psychological factors between H+/D- and H-/D- groups; in fact, individuals 56-65 years in the H+/D- group endorsed aging the most successfully. Small sample size within the groups and the cross-sectional nature of the analysis limit the ability to address onset of depressive symptoms in relation to HRQoL or positive psychological factors. Among PLWH depressive symptoms show a strong association with HRQoL and positive psychological factors compared to HIV- individuals. In the absence of elevated depressive symptoms, however, PLWH report similar HRQoL and positive psychological factors to HIV- individuals.
Sections du résumé
BACKGROUND
Depression is prevalent among persons living with HIV (PLWH). This study investigated the relationships between depressive symptomatology, health-related quality of life (HRQoL), and positive psychological factors in PLWH and age-matched HIV-individuals.
METHODS
One hundred twenty-two PLWH and 94 HIV- individuals, recruited in three age cohorts (36-45, 46-55, 56-65 years old), completed self-report questionnaires on depressive symptoms (CES-D), HRQoL, and positive psychological factors (resilience, grit, and self-rated successful aging [SRSA]). Participants were classified based on HIV status (H+ vs H-) and elevated depressive symptoms (D+ vs D-) into four groups (H+/D+; H-/D+; H+/D-; H-/D-).
RESULTS
Fifty-eight percent of PLWH had elevated depressive scores, compared to 33% of HIV- individuals (p < 0.001). The proportion of individuals reporting elevated depressive symptoms only differed among individuals 36-45 years old (H+: 61.5%; H-: 17.9%; p < 0.001). Individuals in the H+/D+ group reported the lowest HRQoL, resilience, grit, and SRSA across age cohorts. However, there were no differences on HRQoL or positive psychological factors between H+/D- and H-/D- groups; in fact, individuals 56-65 years in the H+/D- group endorsed aging the most successfully.
LIMITATIONS
Small sample size within the groups and the cross-sectional nature of the analysis limit the ability to address onset of depressive symptoms in relation to HRQoL or positive psychological factors.
CONCLUSIONS
Among PLWH depressive symptoms show a strong association with HRQoL and positive psychological factors compared to HIV- individuals. In the absence of elevated depressive symptoms, however, PLWH report similar HRQoL and positive psychological factors to HIV- individuals.
Identifiants
pubmed: 30884371
pii: S0165-0327(18)31672-0
doi: 10.1016/j.jad.2019.03.025
pmc: PMC6705595
mid: NIHMS1524175
pii:
doi:
Types de publication
Comparative Study
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-7Subventions
Organisme : NIAAA NIH HHS
ID : T32 AA013525
Pays : United States
Organisme : NIMH NIH HHS
ID : K23 MH107260
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG062387
Pays : United States
Organisme : NIMH NIH HHS
ID : P30 MH062512
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH099987
Pays : United States
Informations de copyright
Copyright © 2019. Published by Elsevier B.V.
Références
Aust N Z J Psychiatry. 1999 Jun;33(3):344-52
pubmed: 10442790
J Clin Epidemiol. 2001 Dec;54 Suppl 1:S44-52
pubmed: 11750209
Gen Hosp Psychiatry. 2002 Jan-Feb;24(1):43-7
pubmed: 11814533
Am J Psychiatry. 2002 Oct;159(10):1752-9
pubmed: 12359683
AIDS. 2004 Jan 1;18 Suppl 1:S43-8
pubmed: 15075497
AIDS Care. 2004 Jul;16(5):649-61
pubmed: 15223534
Med Care. 1992 Jun;30(6):473-83
pubmed: 1593914
AIDS Care. 2005 May;17(4):505-15
pubmed: 16036236
J Gen Intern Med. 2006 Mar;21(3):267-75
pubmed: 16336622
AIDS Care. 2006 Feb;18(2):93-100
pubmed: 16338766
Am J Geriatr Psychiatry. 2006 Jan;14(1):43-51
pubmed: 16407581
AIDS Patient Care STDS. 2007 May;21(5):347-55
pubmed: 17518527
J Pers Soc Psychol. 2007 Jun;92(6):1087-101
pubmed: 17547490
Psychiatr Q. 2008 Mar;79(1):43-53
pubmed: 18095166
J Trauma Stress. 2007 Dec;20(6):1019-28
pubmed: 18157881
J Psychiatr Res. 2008 Dec;43(2):148-54
pubmed: 18455190
Psychosom Med. 2008 Jun;70(5):539-45
pubmed: 18519880
Med Care. 1991 Aug;29(8):786-98
pubmed: 1875745
Curr HIV/AIDS Rep. 2008 Nov;5(4):163-71
pubmed: 18838056
J Pers Assess. 2009 Mar;91(2):166-74
pubmed: 19205937
AIDS Care. 2010 May;22(5):630-9
pubmed: 20401765
J Assoc Nurses AIDS Care. 2011 Jan-Feb;22(1):17-25
pubmed: 20471864
J Affect Disord. 2011 Mar;129(1-3):126-42
pubmed: 20926139
J Affect Disord. 2012 Feb;136(3):993-9
pubmed: 21784531
Psychol Health Med. 2011 Oct;16(5):493-527
pubmed: 21809936
AIDS Care. 2012;24(12):1504-13
pubmed: 22530794
J Acquir Immune Defic Syndr. 2012 Jul 1;60 Suppl 1:S1-18
pubmed: 22688010
Lancet. 2013 Feb 2;381(9864):375-84
pubmed: 23219570
Am J Psychiatry. 2013 Feb;170(2):188-96
pubmed: 23223917
Psychiatry Clin Neurosci. 2014 Feb;68(2):96-109
pubmed: 24552630
Iran J Psychiatry Behav Sci. 2013 Spring;7(1):61-8
pubmed: 24644501
AIDS Behav. 2015 Aug;19(8):1379-87
pubmed: 25085079
J Affect Disord. 2015 Apr 1;175:475-80
pubmed: 25679203
AIDS Care. 2015;27(8):934-45
pubmed: 25782603
AIDS Behav. 2017 Jun;21(6):1684-1690
pubmed: 27864625
Appl Nurs Res. 2017 Feb;33:138-141
pubmed: 28096007
AIDS Care. 2017 Sep;29(9):1178-1185
pubmed: 28127989
Prim Care Companion CNS Disord. 2017 Feb 2;19(1):
pubmed: 28157277
PLoS One. 2017 Aug 24;12(8):e0183614
pubmed: 28837678
AIDS Behav. 2018 May;22(5):1688-1698
pubmed: 29159595
AIDS Behav. 2018 May;22(5):1551-1561
pubmed: 29264737
AIDS Behav. 2018 Oct;22(10):3214-3225
pubmed: 29455265
Med Care. 1995 Apr;33(4 Suppl):AS264-79
pubmed: 7723455
J Psychiatr Res. 1994 Jan-Feb;28(1):57-84
pubmed: 8064641
JAMA. 1993 Feb 10;269(6):729-30
pubmed: 8093740
NIDA Res Monogr. 1997;172:130-55
pubmed: 9154269
Psychol Aging. 1997 Jun;12(2):277-87
pubmed: 9189988
Clin Infect Dis. 1998 Jan;26(1):20-6
pubmed: 9455505