Adverse childhood experiences, mental health, substance use, and HIV-related outcomes among persons with HIV.


Journal

AIDS care
ISSN: 1360-0451
Titre abrégé: AIDS Care
Pays: England
ID NLM: 8915313

Informations de publication

Date de publication:
10 2019
Historique:
pubmed: 20 3 2019
medline: 11 3 2020
entrez: 20 3 2019
Statut: ppublish

Résumé

While persons with HIV (PWH) have benefited from significant advances in treatment and resulting longevity, mental health problems remain elevated in this population. Adverse childhood experiences (ACEs) are common among PWH and may negatively affect mental health and HIV-related outcomes. We examined the association between ACEs, depression and anxiety symptoms, substance use, antiretroviral therapy (ART) adherence, and HIV-clinical indicators in a sample of 584 PWH at risk for unhealthy alcohol use enrolled in a primary care-based alcohol intervention study. The sample was 96.9% male, 63.0% non-Hispanic white, with an average age of 49.0 years. ACEs were highly prevalent: 82.5% reported ≥1 ACE, including 34.2% reporting 1-2 ACEs, 25.0% reporting 3-4 ACEs, and 23.3% reporting ≥5 ACEs. Adjusting for demographics, having 1-2, 3-4 or ≥5 ACEs was significantly associated with anxiety (ORs (95%CI): 3.41 (1.13-10.33), 4.36 (1.42-3.36), and 3.96 (1.28-12.19), respectively) and poorer mental health quality of life (Betas (SE): -3.21 (1.40), -6.23 (1.51), and -7.09 (1.54), respectively), but not with other outcomes. Trauma-informed interventions to reduce anxiety and improve mental health quality of life in PWH may reduce the negative health sequelae of ACEs.

Identifiants

pubmed: 30887831
doi: 10.1080/09540121.2019.1587372
pmc: PMC6675575
mid: NIHMS1534223
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1241-1249

Subventions

Organisme : NIDA NIH HHS
ID : K01 DA043604
Pays : United States
Organisme : NIAAA NIH HHS
ID : K24 AA025703
Pays : United States
Organisme : NIAAA NIH HHS
ID : U01 AA021997
Pays : United States

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Auteurs

Kelly C Young-Wolff (KC)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.
b Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California , San Francisco , CA , USA.

Varada Sarovar (V)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.

Stacy A Sterling (SA)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.

Amy Leibowitz (A)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.

Brigid McCaw (B)

c Family Violence Prevention Program, Kaiser Permanente , Oakland , CA , USA.

Charles B Hare (CB)

d Department of Adult and Family Medicine, Kaiser Permanente San Francisco Medical Center , San Francisco , CA , USA.

Michael J Silverberg (MJ)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.

Derek D Satre (DD)

a Division of Research, Kaiser Permanente , Oakland , CA , USA.
b Department of Psychiatry, UCSF Weill Institute for Neurosciences, University of California , San Francisco , CA , USA.

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