Rates of Cardiac Rhythm Abnormalities in Patients with CKD and Diabetes.
Atrial Fibrillation
Cardiac Conduction System Disease
Diabetes Mellitus, Type 2
Heart Atria
Prospective Studies
Renal Insufficiency, Chronic
Ventricular Premature Complexes
cardiovascular disease
electrophysiology
glomerular filtration rate
renal dialysis
Journal
Clinical journal of the American Society of Nephrology : CJASN
ISSN: 1555-905X
Titre abrégé: Clin J Am Soc Nephrol
Pays: United States
ID NLM: 101271570
Informations de publication
Date de publication:
05 04 2019
05 04 2019
Historique:
received:
05
08
2018
accepted:
18
01
2019
pubmed:
21
3
2019
medline:
10
7
2020
entrez:
21
3
2019
Statut:
ppublish
Résumé
Cardiac arrhythmias increase mortality and morbidity in CKD. We evaluated the rates of subclinical arrhythmias in a population with type 2 diabetes and patients with moderate to severe CKD who were not on dialysis. This is a prospective observational study, using continuous ambulatory cardiac monitors to determine the rate of atrial and ventricular arrhythmias, as well as conduction abnormalities in this group. A total of 38 patients (34% women), with mean eGFR of 38±13 ml/min per 1.73 m Cardiac rhythm abnormalities are common in patients with diabetes with moderate to severe CKD not requiring dialysis. Rates of atrial fibrillation are high and episodes are asymptomatic. Future studies are needed to determine the role of screening and upstream therapy of cardiac arrhythmias in this group.
Sections du résumé
BACKGROUND AND OBJECTIVES
Cardiac arrhythmias increase mortality and morbidity in CKD. We evaluated the rates of subclinical arrhythmias in a population with type 2 diabetes and patients with moderate to severe CKD who were not on dialysis.
DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS
This is a prospective observational study, using continuous ambulatory cardiac monitors to determine the rate of atrial and ventricular arrhythmias, as well as conduction abnormalities in this group.
RESULTS
A total of 38 patients (34% women), with mean eGFR of 38±13 ml/min per 1.73 m
CONCLUSIONS
Cardiac rhythm abnormalities are common in patients with diabetes with moderate to severe CKD not requiring dialysis. Rates of atrial fibrillation are high and episodes are asymptomatic. Future studies are needed to determine the role of screening and upstream therapy of cardiac arrhythmias in this group.
Identifiants
pubmed: 30890578
pii: 01277230-201904000-00012
doi: 10.2215/CJN.09420818
pmc: PMC6450349
doi:
Types de publication
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
549-556Subventions
Organisme : NIDDK NIH HHS
ID : P30 DK017047
Pays : United States
Informations de copyright
Copyright © 2019 by the American Society of Nephrology.
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