Retinal structural-vascular-functional relationship using optical coherence tomography and optical coherence tomography - angiography in myopia.

BACKGROUND

To examine the retinal structure-vascular-function relationship using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in myopia.

METHODS

This was a prospective cross-sectional study comprising 86 eyes of 45 individuals with varying axial lengths and spherical equivalents and no posterior segment abnormalities. All eyes underwent optical coherence tomography with the Spectralis SD-OCT and OCTA with RTVue-XR Avanti; Optovue. Individual macular retinal layer thicknesses and flow areas and vessel densities were measured on OCT and OCTA, respectively. Linear correlations were made between the macular layer thicknesses, flow areas and vessel densities with axial length, spherical equivalent and visual acuity.

RESULTS

The participants' mean ages were 33.34 ± 14.45 years, mean spherical equivalent refractions were - 7.17 ± 5.71 D and axial lengths were 25.95 ± 2.41 mm. There were significant positive correlations of foveal angle (r = 0.757,

CONCLUSION

The lateral retinal stretching in myopia could possibly explain the correlation between retinal layer thickness, vascular density and visual acuity in these eyes. Further research is required to investigate this.

Déclaration de conflit d'intérêts

Approval was obtained from the Institutional review board and Ethics committee (ECR/187/Inst/Kar/2013/RR-16).The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his/her images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published, and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.The authors declare that they have no competing interests.