Anti-VEGF drug interference with VEGF quantitation in the R&D systems human quantikine VEGF ELISA kit.


Journal

Bioanalysis
ISSN: 1757-6199
Titre abrégé: Bioanalysis
Pays: England
ID NLM: 101512484

Informations de publication

Date de publication:
Mar 2019
Historique:
pubmed: 21 3 2019
medline: 28 7 2019
entrez: 21 3 2019
Statut: ppublish

Résumé

To evaluate the accuracy of the Quantikine Human VEGF Immunoassay (R&D Systems) in the presence of VEGF inhibitors. Quantikine VEGF ELISA (R&D), anti-VEGF Binding affinity of anti-VEGF The immunoassay cannot accurately quantitate VEGF in the presence of these VEGF inhibitors as they interfere with the capture and detection of free VEGF.

Identifiants

pubmed: 30892063
doi: 10.4155/bio-2018-0096
doi:

Substances chimiques

Angiogenesis Inhibitors 0
Vascular Endothelial Growth Factor A 0

Types de publication

Journal Article

Langues

eng

Pagination

381-392

Auteurs

Giane Sumner (G)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Camille Georgaros (C)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Ashique Rafique (A)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Thomas DiCioccio (T)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Joel Martin (J)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Nicholas Papadopoulos (N)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Thomas Daly (T)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Albert Torri (A)

Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

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Classifications MeSH