The potential role of auditory prediction error in decompensated tinnitus: An auditory mismatch negativity study.


Journal

Brain and behavior
ISSN: 2162-3279
Titre abrégé: Brain Behav
Pays: United States
ID NLM: 101570837

Informations de publication

Date de publication:
04 2019
Historique:
received: 25 09 2018
revised: 08 12 2018
accepted: 10 12 2018
pubmed: 22 3 2019
medline: 25 12 2019
entrez: 22 3 2019
Statut: ppublish

Résumé

Some tinnitus subjects habituate to their tinnitus but some others do not and complain of its annoyance tremendously. Normal sensory memory and change detection processes are needed for detecting the tinnitus signal as a prediction error and habituation to tinnitus. The purpose of this study was to compare auditory mismatch negativity as the index of sensory memory and change detection among the studied groups to search for the factors involving in the perception of tinnitus and preventing habituation in decompensated tinnitus subjects. Electroencephalography was recorded from scalp electrodes in compensated tinnitus, decompensated tinnitus, and no tinnitus control subjects. Mismatch negativity was obtained using the oddball paradigm with frequency, duration, and silent gap deviants. Amplitude, latency, and area under the curve of mismatch negativities were compared among the three studied groups. The results showed lower mismatch negativity amplitude and area under the curve for the higher frequency deviant and for the silent gap deviant in decompensated tinnitus group compared to normal control and compensated tinnitus group. This study revealed a deficit in sensory memory and change detection processing in decompensated tinnitus subjects. This causes persistent prediction errors; tinnitus signal is consistently detected as a new signal and activates the brain salience network and consequently prevents habituation to tinnitus. Mismatch negativity is proposed as an index for monitoring tinnitus rehabilitation.

Identifiants

pubmed: 30895749
doi: 10.1002/brb3.1242
pmc: PMC6456780
doi:

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e01242

Subventions

Organisme : Iran Ministry of health
ID : 271/7.11.2016
Pays : International

Informations de copyright

© 2019 The Authors. Brain and Behavior published by Wiley Periodicals, Inc.

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Auteurs

Mehrnaz Mohebbi (M)

ENT and Head & Neck Research Center and Department, The Five Senses Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Ahmad Daneshi (A)

ENT and Head & Neck Research Center and Department, The Five Senses Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Abdoreza Asadpour (A)

Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran.

Samer Mohsen (S)

Department of Otolaryngology, Faculty of Medicine, Damascus University, Damascus, Syria.

Mohammad Farhadi (M)

ENT and Head & Neck Research Center and Department, The Five Senses Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Saeid Mahmoudian (S)

ENT and Head & Neck Research Center and Department, The Five Senses Institute, Hazrat Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Department of Otorhinolaryngology, Hannover Medical University (MHH), Hannover, Germany.

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