Subclonal STAT3 mutations solidify clonal dominance.

Case-Control Studies Clone Cells Humans Leukemia, Large Granular Lymphocytic / pathology Mutation Receptors, Antigen, T-Cell STAT3 Transcription Factor / genetics T-Lymphocytes, Cytotoxic / cytology

Journal

Blood advances
ISSN: 2473-9537
Titre abrégé: Blood Adv
Pays: United States
ID NLM: 101698425

Informations de publication

Date de publication:
26 03 2019
Historique:
received: 29 10 2018
accepted: 20 01 2019
entrez: 23 3 2019
pubmed: 23 3 2019
medline: 28 3 2020
Statut: ppublish

Résumé

T large granular lymphocyte leukemia (T-LGLL) is a clonal lymphoproliferative disorder that can arise in the context of pathologic or physiologic cytotoxic T-cell (CTL) responses.

Identifiants

DOI: 10.1182/bloodadvances.2018027862 PMID: 30898763 PMC: PMC6436009
pubmed: 30898763
pii: bloodadvances.2018027862
doi: 10.1182/bloodadvances.2018027862
pmc: PMC6436009
doi:

Substances chimiques

Receptors, Antigen, T-Cell 0
STAT3 Transcription Factor 0
STAT3 protein, human 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

917-921

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL118281
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL123904
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL132071
Pays : United States
Organisme : NHLBI NIH HHS
ID : R35 HL135795
Pays : United States

Informations de copyright

© 2019 by The American Society of Hematology.

Références

Blood. 2011 Oct 20;118(16):4384-93
pubmed: 21865345
Blood. 2012 Oct 11;120(15):3048-57
pubmed: 22859607
Blood. 2011 Mar 10;117(10):2764-74
pubmed: 21190991
Leuk Lymphoma. 2015 Feb;56(2):324-31
pubmed: 24828862
N Engl J Med. 2012 May 17;366(20):1905-13
pubmed: 22591296
Ann Med. 2014 May;46(3):114-22
pubmed: 24512550
Blood. 2016 May 19;127(20):2375-90
pubmed: 26980727
Leuk Lymphoma. 2018 Feb;59(2):416-422
pubmed: 28633612
Blood. 2013 Dec 12;122(25):4077-85
pubmed: 24149287
J Clin Invest. 2001 Feb;107(3):351-62
pubmed: 11160159
Leukemia. 2016 May;30(5):1204-8
pubmed: 26419508
Leukemia. 2013 Jul;27(7):1598-600
pubmed: 23207521
Hematology. 2006 Aug;11(4):245-56
pubmed: 17178663
Haematologica. 2015 Jan;100(1):91-9
pubmed: 25281507
Blood. 2017 Mar 2;129(9):1082-1094
pubmed: 28115367
Ann Intern Med. 1985 Feb;102(2):169-75
pubmed: 3966754
Blood. 1987 Jun;69(6):1786
pubmed: 3580580
Oncologist. 2006 Mar;11(3):263-73
pubmed: 16549811

Auteurs

Cassandra M Kerr (CM)

Department of Translational Hematology and Oncology Research and.

Michael J Clemente (MJ)

Department of Translational Hematology and Oncology Research and.

Peter W Chomczynski (PW)

Department of Translational Hematology and Oncology Research and.

Bartlomiej Przychodzen (B)

Department of Translational Hematology and Oncology Research and.

Yasunobu Nagata (Y)

Department of Translational Hematology and Oncology Research and.

Vera Adema (V)

Department of Translational Hematology and Oncology Research and.

Valeria Visconte (V)

Department of Translational Hematology and Oncology Research and.

Alan E Lichtin (AE)

Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.

Satu Mustjoki (S)

Hematology Research Unit Helsinki, University of Helsinki, Helsinki, Finland.
Department of Hematology, Helsinki University Hospital Comprehensive Cancer Centre, Helsinki, Finland; and.
ORCID: 0000-0002-0816-8241

Tomas Radivoyevitch (T)

Quantitative Health Sciences Department, Cleveland Clinic, Cleveland, OH.

Mikkael A Sekeres (MA)

Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.

Jaroslaw P Maciejewski (JP)

Department of Translational Hematology and Oncology Research and.
Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études cas-témoins › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Cellules › Cellules cultivées › Clones cellulaires › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Leucémie lymphoïde › Leucémie à cellules T › Leucémie à grands lymphocytes granuleux › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › Facteurs de transcription STAT › Facteur de transcription STAT-3 › Subclonal STAT3 mutations solidify clonal dominance.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T cytotoxiques › Subclonal STAT3 mutations solidify clonal dominance.