Neurocognitive Functions in Infants with Malnutrition; Relation with Long-chain Polyunsaturated Fatty Acids, Micronutrients Levels and Magnetic Resonance Spectroscopy.
Calcium
Fatty acids, unsaturated
Malnutrition
Neurocognitive
Spectroscopy
Journal
Pediatric gastroenterology, hepatology & nutrition
ISSN: 2234-8646
Titre abrégé: Pediatr Gastroenterol Hepatol Nutr
Pays: Korea (South)
ID NLM: 101590471
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
26
04
2018
revised:
08
08
2018
accepted:
01
09
2018
entrez:
23
3
2019
pubmed:
23
3
2019
medline:
23
3
2019
Statut:
ppublish
Résumé
Malnutrition may influence neurocognitive development in children by directly affecting the brain structural development, or indirectly by affecting the children's cognition experience. Malnutrition alters the cell numbers, cell migration, synaptogenesis, and neurotransmission due to inadequate availability of necessary micronutrients to support cell growth. We aimed to analyze neurocognitive development in infants with malnutrition and its association with long chain polyunsaturated fatty acids (LC-PUFA), micronutrients levels and magnetic resonance spectroscopy (MRS) findings. The study included two groups; group 1, infants with malnutrition (n=24), group 2; healthy infants (n=21). Peripheral blood was obtained from the participants for studying micronutrients and LC-PUFA levels. The neurocognitive development was analyzed by the use of an Ankara Developmental Screening Inventory test. MRS were performed on all infants. All parameters of neurocognitive development and serum calcium (9.6±0.9 mg/dL vs. 10.4±0.3 mg/dL, Calcium supplementation may improve neurocognitive development in malnourished infants.
Identifiants
pubmed: 30899693
doi: 10.5223/pghn.2019.22.2.171
pii: 2019220207
pmc: PMC6416383
doi:
Types de publication
Journal Article
Langues
eng
Pagination
171-180Déclaration de conflit d'intérêts
Conflict of Interest: The authors have no financial conflicts of interest.
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