The Protein Phosphorylation Landscape of Mouse Spermatids during Spermiogenesis.

Animals Male Mice Phosphopeptides / analysis Phosphoproteins / analysis Phosphorylation Protein Kinases / analysis Proteins / analysis Proteomics Spermatids / cytology Spermatogenesis
mouse phosphoproteome phosphorylation spermatid spermiogenesis

Journal

Proteomics
ISSN: 1615-9861
Titre abrégé: Proteomics
Pays: Germany
ID NLM: 101092707

Informations de publication

Date de publication:
06 2019
Historique:
received: 03 02 2019
pubmed: 23 3 2019
medline: 29 4 2020
entrez: 23 3 2019
Statut: ppublish

Résumé

The characteristic tadpole shape of sperm is formed from round spermatids via spermiogenesis, a process which results in dramatic morphological changes in the final stage of spermatogenesis in the testis. Protein phosphorylation, as one of the most important post-translational modifications, can regulate spermiogenesis; however, the phosphorylation events taking place during this process have not been systematically analyzed. In order to better understand the role of phosphorylation in spermiogenesis, large-scale phosphoproteome profiling is performed using IMAC and TiO

Identifiants

DOI: 10.1002/pmic.201900055 PMID: 30901149
pubmed: 30901149
doi: 10.1002/pmic.201900055
doi:

Substances chimiques

Phosphopeptides 0
Phosphoproteins 0
Proteins 0
Protein Kinases EC 2.7.-

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1900055

Informations de copyright

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Auteurs

Yan Li (Y)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.
Center of Pathology and Clinical Laboratory, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, 211166, China.

Yiwei Cheng (Y)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Tianyu Zhu (T)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Hao Zhang (H)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Wen Li (W)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Yueshuai Guo (Y)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Yaling Qi (Y)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Xu Chen (X)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Jun Zhang (J)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Jiahao Sha (J)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Zuomin Zhou (Z)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Hui Zhu (H)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.

Xuejiang Guo (X)

State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, 210029, China.
ORCID: 0000-0002-0475-5705

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Phosphopeptides › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Phosphoprotéines › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Métabolisme › Phosphorylation › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Phosphotransferases › Phosphotransferases (Alcohol Group Acceptor) › Protein kinases › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Disciplines des sciences naturelles › Chimie › Biochimie › Protéomique › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Cellules › Cellules germinales › Spermatozoïdes › Spermatides › The Protein Phosphorylation Landscape of Mouse...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Gamétogenèse › Spermatogenèse › The Protein Phosphorylation Landscape of Mouse...