Occupation and motor neuron disease: a New Zealand case-control study.
Adult
Aged
Agriculture
/ statistics & numerical data
Case-Control Studies
Female
Humans
Industry
/ statistics & numerical data
Logistic Models
Male
Middle Aged
Motor Neuron Disease
/ diagnosis
New Zealand
/ epidemiology
Occupations
/ statistics & numerical data
Population Surveillance
/ methods
Registries
/ statistics & numerical data
Risk Factors
epidemiology
public health
Journal
Occupational and environmental medicine
ISSN: 1470-7926
Titre abrégé: Occup Environ Med
Pays: England
ID NLM: 9422759
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
23
11
2018
revised:
15
02
2019
accepted:
25
02
2019
pubmed:
25
3
2019
medline:
3
1
2020
entrez:
24
3
2019
Statut:
ppublish
Résumé
To assess associations between occupation and motor neuron disease (MND). We conducted a population-based case-control study with cases (n=321) recruited through the New Zealand Motor Neurone Disease Association and hospital discharge data. Controls (n=605) were recruited from the Electoral Roll. Information on personal and demographic details, lifestyle factors and a full occupational history was collected using questionnaires and interviews. Associations with ever/never employed and employment duration were estimated using logistic regression stratified by sex and adjusted for age, ethnicity, socioeconomic deprivation, education and smoking. Elevated risks were observed for field crop and vegetable growers (OR 2.93, 95% CI 1.10 to 7.77); fruit growers (OR 2.03, 95% CI 1.09 to 3.78); gardeners and nursery growers (OR 1.96, 95% CI 1.01 to 3.82); crop and livestock producers (OR 3.61, 95% CI 1.44 to 9.02); fishery workers, hunters and trappers (OR 5.62, 95% CI 1.27 to 24.97); builders (OR 2.90, 95% CI 1.41 to 5.96); electricians (OR 3.61, 95% CI 1.34 to 9.74); caregivers (OR 2.65, 95% CI 1.04 to 6.79); forecourt attendants (OR 8.31, 95% CI 1.79 to 38.54); plant and machine operators and assemblers (OR 1.42, 95% CI 1.01 to 2.01); telecommunications technicians (OR 4.2, 95% CI 1.20 to 14.64); and draughting technicians (OR 3.02, 95% CI 1.07 to 8.53). Industries with increased risks were agriculture (particularly horticulture and fruit growing), construction, non-residential care services, motor vehicle retailing, and sport and recreation. Positive associations between employment duration and MND were shown for the occupations fruit growers, gardeners and nursery growers, and crop and livestock producers, and for the horticulture and fruit growing industry. This study suggests associations between MND and occupations in agriculture and several other occupations.
Identifiants
pubmed: 30902826
pii: oemed-2018-105605
doi: 10.1136/oemed-2018-105605
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
309-316Informations de copyright
© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.