Male DCIS diagnosed after use of over-the-counter hormonal supplement.
Atypical ductal hyperplasia
Ductal carcinoma in-situ
Gynecomastia
Male breast cancer
Mastectomy
Journal
International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872
Informations de publication
Date de publication:
2019
2019
Historique:
received:
16
10
2018
revised:
10
02
2019
accepted:
13
02
2019
pubmed:
25
3
2019
medline:
25
3
2019
entrez:
24
3
2019
Statut:
ppublish
Résumé
Male breast cancer is a rare disease. Although epidemiologic and genetic factors are associated with male breast cancer, hormonal factors may also play a role. We report the case of a 39-year-old BRCA negative male patient taking a sexual performance enhancement supplement who presented with worsening asymmetric gynecomastia and unilateral spontaneous bloody nipple discharge and was found to have ductal carcinoma in-situ. The altered cellular environment related to the hormone contents of the supplement coincided with the rapid worsening of his gynecomastia and may have played a role in the development of the ductal carcinoma in-situ, or growth of an existing focus. The use of hormonal male enhancement supplements can lead to higher levels of androgens in users. It is possible for this altered hormonal environment to cause the growth of tumor or promote the progression of an existing focus.
Identifiants
pubmed: 30903856
pii: S2210-2612(19)30089-6
doi: 10.1016/j.ijscr.2019.02.028
pmc: PMC6430715
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
60-62Informations de copyright
Copyright © 2019. Published by Elsevier Ltd.
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