[Treatment of patients with brain metastases from a melanoma].
Prise en charge des patients atteints de métastases cérébrales de mélanome.
Antineoplastic Agents, Immunological
/ therapeutic use
Brain
/ pathology
Brain Neoplasms
/ pathology
CTLA-4 Antigen
/ antagonists & inhibitors
Dose Fractionation, Radiation
Humans
Melanoma
/ pathology
Mutation
Necrosis
/ etiology
Programmed Cell Death 1 Receptor
/ antagonists & inhibitors
Proto-Oncogene Proteins B-raf
/ genetics
Radiosurgery
Skin Neoplasms
/ pathology
Anti-BRAF treatment
Brain metastases
Chirurgie
Immune check point inhibitors
Immunothérapie
Metastatic melanoma
Mélanome métastatique
Métastases cérébrales
Radiothérapie
Stereotactic radiotherapy
Stéréotaxie
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
ISSN: 1769-6658
Titre abrégé: Cancer Radiother
Pays: France
ID NLM: 9711272
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
22
01
2018
revised:
15
05
2018
accepted:
17
05
2018
pubmed:
25
3
2019
medline:
10
5
2019
entrez:
25
3
2019
Statut:
ppublish
Résumé
Whereas immune checkpoint inhibitors of serine/threonine protein kinase B-raf therapy dramatically changed metastatic outcomes of patients with melanoma, they remain at high risk of brain extension. Additional local treatment can be offered in this situation such as surgery and or stereotactic radiotherapy. In this review article, we describe the different options with published data and their optimal timing.
Identifiants
pubmed: 30904418
pii: S1278-3218(19)30021-6
doi: 10.1016/j.canrad.2018.05.006
pii:
doi:
Substances chimiques
Antineoplastic Agents, Immunological
0
CTLA-4 Antigen
0
PDCD1 protein, human
0
Programmed Cell Death 1 Receptor
0
BRAF protein, human
EC 2.7.11.1
Proto-Oncogene Proteins B-raf
EC 2.7.11.1
Types de publication
Journal Article
Review
Langues
fre
Sous-ensembles de citation
IM
Pagination
147-150Informations de copyright
Copyright © 2019 Société française de radiothérapie oncologique (SFRO). Published by Elsevier Masson SAS. All rights reserved.