Growth factor sustained delivery from poly-lactic-co-glycolic acid microcarriers and its mass transfer modeling by finite element in a dynamic and static three-dimensional environment bioengineered with stem cells.
3D alginate scaffold
FEM modeling
PLGA microcarriers
growth factor controlled delivery
growth factor mass transfer
human mesenchymal stem cells
human morphogenetic protein 2
microenvironment formulation
Journal
Biotechnology and bioengineering
ISSN: 1097-0290
Titre abrégé: Biotechnol Bioeng
Pays: United States
ID NLM: 7502021
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
12
12
2018
revised:
18
02
2019
accepted:
21
03
2019
pubmed:
25
3
2019
medline:
3
7
2020
entrez:
25
3
2019
Statut:
ppublish
Résumé
Poly-lactic-co-glycolic acid (PLGA) microcarriers (0.8 ± 0.2 μm) have been fabricated with a load of 20 μg/g
Substances chimiques
BMP2 protein, human
0
Bone Morphogenetic Protein 2
0
Delayed-Action Preparations
0
Drug Carriers
0
Hydrogels
0
Polylactic Acid-Polyglycolic Acid Copolymer
1SIA8062RS
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1777-1794Informations de copyright
© 2019 Wiley Periodicals, Inc.