Glycolytic Enzyme PKM2 Mediates Autophagic Activation to Promote Cell Survival in NPM1-Mutated Leukemia.
Adult
Autophagy
/ genetics
Carrier Proteins
Cell Line, Tumor
Cell Survival
/ genetics
Female
Flow Cytometry
Humans
Leukemia, Myeloid, Acute
/ genetics
Male
Membrane Proteins
Middle Aged
Mutation
/ genetics
Nuclear Proteins
/ genetics
Nucleophosmin
Phosphorylation
/ genetics
Real-Time Polymerase Chain Reaction
Thyroid Hormones
Thyroid Hormone-Binding Proteins
Acute myeloid leukemia
Autophagy
Cell survival
Nucleophosmin
PKM2
PTBP1
Journal
International journal of biological sciences
ISSN: 1449-2288
Titre abrégé: Int J Biol Sci
Pays: Australia
ID NLM: 101235568
Informations de publication
Date de publication:
2019
2019
Historique:
received:
29
09
2018
accepted:
12
01
2019
entrez:
26
3
2019
pubmed:
25
3
2019
medline:
6
2
2020
Statut:
epublish
Résumé
Acute myeloid leukemia (AML) with mutated
Identifiants
pubmed: 30906218
doi: 10.7150/ijbs.30290
pii: ijbsv15p0882
pmc: PMC6429014
doi:
Substances chimiques
Carrier Proteins
0
Membrane Proteins
0
NPM1 protein, human
0
Nuclear Proteins
0
Thyroid Hormones
0
Nucleophosmin
117896-08-9
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
882-894Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interest exists.
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