Best Buy in Public Health or Luxury Expense?: The Cost-effectiveness of a Pediatric Operating Room in Uganda From the Societal Perspective.


Journal

Annals of surgery
ISSN: 1528-1140
Titre abrégé: Ann Surg
Pays: United States
ID NLM: 0372354

Informations de publication

Date de publication:
01 02 2021
Historique:
pubmed: 26 3 2019
medline: 20 2 2021
entrez: 26 3 2019
Statut: ppublish

Résumé

To determine the cost-effectiveness of building and maintaining a dedicated pediatric operating room (OR) in Uganda from the societal perspective. Despite the heavy burden of pediatric surgical disease in low-income countries, definitive treatment is limited as surgical infrastructure is inadequate to meet the need, leading to preventable morbidity and mortality in children. In this economic model, we used a decision tree template to compare the intervention of a dedicated pediatric OR in Uganda for a year versus the absence of a pediatric OR. Costs were included from the government, charity, and patient perspectives. OR and ward case-log informed epidemiological and patient outcomes data, and measured cost per disability adjusted life year averted and cost per life saved. The incremental cost-effectiveness ratio (ICER) was calculated between the intervention and counterfactual scenario. Costs are reported in 2015 US$ and inflated by 5.5%. In Uganda, the implementation of a dedicated pediatric OR has an ICER of $37.25 per disability adjusted life year averted or $3321 per life saved, compared with no existing operating room. The ICER is well below multiple cost-effectiveness thresholds including one times the country's gross domestic product per capita ($694). The ICER remained robust under 1-way and probabilistic sensitivity analyses. Our model ICER suggests that the construction and maintenance of a dedicated pediatric operating room in sub-Saharan Africa is very-cost effective if hospital space and personnel pre-exist to staff the facility. This supports infrastructure implementation for surgery in sub-Saharan Africa as a worthwhile investment.

Sections du résumé

OBJECTIVE
To determine the cost-effectiveness of building and maintaining a dedicated pediatric operating room (OR) in Uganda from the societal perspective.
BACKGROUND
Despite the heavy burden of pediatric surgical disease in low-income countries, definitive treatment is limited as surgical infrastructure is inadequate to meet the need, leading to preventable morbidity and mortality in children.
METHODS
In this economic model, we used a decision tree template to compare the intervention of a dedicated pediatric OR in Uganda for a year versus the absence of a pediatric OR. Costs were included from the government, charity, and patient perspectives. OR and ward case-log informed epidemiological and patient outcomes data, and measured cost per disability adjusted life year averted and cost per life saved. The incremental cost-effectiveness ratio (ICER) was calculated between the intervention and counterfactual scenario. Costs are reported in 2015 US$ and inflated by 5.5%.
FINDINGS
In Uganda, the implementation of a dedicated pediatric OR has an ICER of $37.25 per disability adjusted life year averted or $3321 per life saved, compared with no existing operating room. The ICER is well below multiple cost-effectiveness thresholds including one times the country's gross domestic product per capita ($694). The ICER remained robust under 1-way and probabilistic sensitivity analyses.
CONCLUSION
Our model ICER suggests that the construction and maintenance of a dedicated pediatric operating room in sub-Saharan Africa is very-cost effective if hospital space and personnel pre-exist to staff the facility. This supports infrastructure implementation for surgery in sub-Saharan Africa as a worthwhile investment.

Identifiants

pubmed: 30907755
pii: 00000658-202102000-00026
doi: 10.1097/SLA.0000000000003263
pmc: PMC6752983
mid: NIHMS1021952
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

379-386

Subventions

Organisme : NIAID NIH HHS
ID : K01 AI119603
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Informations de copyright

Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

The authors disclose no conflicts of interest.

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Auteurs

Ava Yap (A)

Department of Surgery, University of California San Francisco, San Francisco, CA.

Maija Cheung (M)

Department of Surgery, Yale University School of Medicine, New Haven, CT.

Arlene Muzira (A)

Department of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.

James Healy (J)

Department of Surgery, Yale University School of Medicine, New Haven, CT.

Nasser Kakembo (N)

Department of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.

Phyllis Kisa (P)

Department of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.

David Cunningham (D)

KidsOR, Edinburgh, Scotland, UK.

George Youngson (G)

KidsOR, Edinburgh, Scotland, UK.

John Sekabira (J)

Department of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.

Reza Yaesoubi (R)

Department of Health Management and Policy, Yale School of Public Health, New Haven, CT.

Doruk Ozgediz (D)

Department of Surgery, Yale University School of Medicine, New Haven, CT.

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