Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome.
Journal
Cell discovery
ISSN: 2056-5968
Titre abrégé: Cell Discov
Pays: England
ID NLM: 101661034
Informations de publication
Date de publication:
2019
2019
Historique:
received:
17
10
2018
revised:
15
01
2019
accepted:
22
01
2019
entrez:
27
3
2019
pubmed:
27
3
2019
medline:
27
3
2019
Statut:
epublish
Résumé
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder for which no cure exists. The disease is characterized by premature aging and inevitable death in adolescence due to cardiovascular complications. Most HGPS patients carry a heterozygous de novo
Identifiants
pubmed: 30911407
doi: 10.1038/s41421-019-0084-z
pii: 84
pmc: PMC6423020
doi:
Types de publication
Journal Article
Langues
eng
Pagination
16Déclaration de conflit d'intérêts
The authors declare that they have no conflict of interest.After acceptance of this article, the authors have generated new HGPS minipigs by SCNT using heterozygous LMNA 1824 C>T Yucatan minipig fibroblasts (in collaboration with Dr. Eckhard Wolf, Ludwig-Maximilians-Universität München, Germany).
Références
Cardiovasc Pathol. 1999 Jan-Feb;8(1):29-39
pubmed: 10722246
Cardiovasc Pathol. 2001 May-Jun;10(3):133-6
pubmed: 11485857
Science. 2003 Jun 27;300(5628):2055
pubmed: 12702809
Nature. 2003 May 15;423(6937):293-8
pubmed: 12714972
J Cell Sci. 2004 Mar 1;117(Pt 7):1173-8
pubmed: 14996939
J Heart Valve Dis. 2004 Sep;13(5):866-9
pubmed: 15473493
N Engl J Med. 2008 Feb 7;358(6):592-604
pubmed: 18256394
Pediatr Cardiol. 2010 Aug;31(6):925-6
pubmed: 20401475
Theriogenology. 2010 Oct 15;74(7):1233-40
pubmed: 20688371
Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9
pubmed: 20798379
Vet Pathol. 2012 Mar;49(2):344-56
pubmed: 21441112
Ann Pediatr Cardiol. 2011 Jul;4(2):204-6
pubmed: 21976890
Sci Transl Med. 2011 Oct 26;3(106):106ra107
pubmed: 22030750
J Inherit Metab Dis. 2012 Jul;35(4):695-713
pubmed: 22453682
J Genet Genomics. 2012 Jun 20;39(6):269-74
pubmed: 22749014
Pediatr Radiol. 2012 Sep;42(9):1089-98
pubmed: 22752073
Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16666-71
pubmed: 23012407
Aging Cell. 2013 Feb;12(1):2-10
pubmed: 23095062
Zygote. 2014 Aug;22(3):356-65
pubmed: 23331714
Nat Biotechnol. 2014 Apr;32(4):347-55
pubmed: 24584096
Circulation. 2014 Jul 1;130(1):27-34
pubmed: 24795390
Cell. 2014 Jun 5;157(6):1262-78
pubmed: 24906146
Proteomics Clin Appl. 2014 Oct;8(9-10):715-31
pubmed: 25092613
Mol Hum Reprod. 2015 Mar;21(3):225-36
pubmed: 25477337
J Am Heart Assoc. 2015 Jan 21;4(1):e001218
pubmed: 25609414
Eur Heart J Cardiovasc Imaging. 2015 Mar;16(3):233-70
pubmed: 25712077
J Cardiovasc Magn Reson. 2015 Feb 19;17:21
pubmed: 25880970
Biochem Soc Trans. 2015 Jun;43(3):508-12
pubmed: 26009199
J Pathol. 2016 Jan;238(2):247-56
pubmed: 26414877
Front Genet. 2015 Sep 16;6:293
pubmed: 26442109
J Pathol. 2016 Jan;238(2):267-87
pubmed: 26446984
Toxicol Pathol. 2016 Apr;44(3):346-57
pubmed: 26511847
J Cardiovasc Magn Reson. 2015 Nov 04;17:92
pubmed: 26538198
Cell Mol Life Sci. 2016 Jul;73(13):2543-63
pubmed: 26755436
Circulation. 2016 Jul 12;134(2):114-25
pubmed: 27400896
Eur Heart J Cardiovasc Imaging. 2016 Dec;17(12):1321-1360
pubmed: 27422899
Hum Genet. 2016 Sep;135(9):1093-105
pubmed: 27432159
Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):E7250-E7259
pubmed: 27799555
Curr Opin Cell Biol. 2017 Jun;46:17-25
pubmed: 28086161
Prog Biophys Mol Biol. 2017 Nov;130(Pt B):394-403
pubmed: 28801038
Annu Rev Physiol. 2018 Feb 10;80:27-48
pubmed: 28934587
Biochem Soc Trans. 2017 Dec 15;45(6):1279-1293
pubmed: 29127216
J Pediatr Adolesc Gynecol. 2018 Jun;31(3):238-241
pubmed: 29258958
JAMA Cardiol. 2018 Apr 1;3(4):326-334
pubmed: 29466530
Circulation. 2018 Jul 17;138(3):266-282
pubmed: 29490993
Nat Commun. 2018 Apr 27;9(1):1700
pubmed: 29703891
JAMA. 2018 Apr 24;319(16):1687-1695
pubmed: 29710166
JAMA Cardiol. 2018 Oct 1;3(10):1024-1025
pubmed: 30046820
J Anim Sci. 1973 May;36(5):927-30
pubmed: 4703721
Yonsei Med J. 1993 Dec;34(4):352-5
pubmed: 8128740