Promoting healthspan and lifespan with caloric restriction in primates.
Journal
Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179
Informations de publication
Date de publication:
2019
2019
Historique:
received:
05
02
2019
accepted:
06
02
2019
entrez:
27
3
2019
pubmed:
27
3
2019
medline:
27
3
2019
Statut:
epublish
Résumé
Recent data confirmed the efficiency of caloric restriction for promoting both healthspan and lifespan in primates, but also revealed potential adverse effects at the central level. This paper proposes perspectives and future directions to counterbalance potential adverse effects. Efforts should be made in combining nutrition-based clinical protocols with therapeutic and/or behavioral interventions to aim for synergetic effects, and therefore delay the onset of age-related diseases without adverse effects.
Identifiants
pubmed: 30911682
doi: 10.1038/s42003-019-0348-z
pii: 348
pmc: PMC6420603
doi:
Types de publication
Journal Article
Langues
eng
Pagination
107Déclaration de conflit d'intérêts
The authors declare no competing interests.
Références
Cell Metab. 2018 Apr 3;27(4):805-815.e4
pubmed: 29576535
ILAR J. 2011;52(1):78-88
pubmed: 21411860
Brain Plast. 2018 Dec 12;4(1):17-52
pubmed: 30564545
Biochim Biophys Acta. 2015 Jun;1852(6):1114-23
pubmed: 25315298
Nature. 2016 Oct 13;538(7624):257-259
pubmed: 27706136
Ageing Res Rev. 2012 Jan;11(1):150-62
pubmed: 21802530
Exp Gerontol. 2013 Oct;48(10):1018-24
pubmed: 23624181
Pharmacol Res. 2014 Dec;90:88-115
pubmed: 25151891
Clin Interv Aging. 2014 Apr 12;9:661-82
pubmed: 24748784
Cell Mol Life Sci. 2015 Apr;72(8):1473-88
pubmed: 25548801
Nat Commun. 2017 Jan 17;8:14063
pubmed: 28094793
Nature. 2017 Jun 28;546(7660):E13-E14
pubmed: 28658239
Age (Dordr). 2011 Mar;33(1):15-31
pubmed: 20532988
Science. 2009 Jul 10;325(5937):201-4
pubmed: 19590001
Nature. 2017 Jun 28;546(7660):E11-E12
pubmed: 28658235
Nature. 2012 Sep 13;489(7415):318-21
pubmed: 22932268
Nature. 2012 Sep 13;489(7415):210-11
pubmed: 22932269
Commun Biol. 2018 Apr 5;1:30
pubmed: 30271916
Ann N Y Acad Sci. 2017 Sep;1403(1):142-149
pubmed: 28815614