Controlling Nutritional Status Score As a Predictive Marker for Patients With Implantable Left Ventricular Assist Device.


Journal

ASAIO journal (American Society for Artificial Internal Organs : 1992)
ISSN: 1538-943X
Titre abrégé: ASAIO J
Pays: United States
ID NLM: 9204109

Informations de publication

Date de publication:
02 2020
Historique:
pubmed: 27 3 2019
medline: 15 9 2020
entrez: 27 3 2019
Statut: ppublish

Résumé

Although a correlation between the nutritional status and the prognosis of patients with heart failure has been suggested, a correlation between the nutritional status and outcomes after the left ventricular assist device (LVAD) implantation remains unclear. We aimed to investigate the efficacy of the Controlling Nutritional Status (CONUT) score (range 0-12, including serum albumin, total cholesterol, and lymphocytes) as a nutritional index in speculating the prognosis of patients undergoing LVAD implantation. We examined 63 consecutive patients who underwent the continuous-flow LVAD implantation. Using the preoperative CONUT score, patients were categorized into two groups: lower CONUT score (0-4: normal to mild malnutrition) and higher CONUT score (5-12: moderate to severe malnutrition). We compared for the backgrounds and the clinical events after LVAD implantation. The higher CONUT group exhibited a significantly higher mean right atrial pressure (10.9 ± 4.7 vs. 7.3 ± 4.1 mmHg; p = 0.0019). In that group, the mortality rate was significantly higher (25% vs. 2.6%; p = 0.0059) and the Kaplan-Meier analysis showed lower survival rate. Furthermore, more bleeding events significantly occurred in the higher CONUT group. The preoperative CONUT score may reflect systemic venous congestion and offer a useful prognostic index of clinical courses after LVAD implantation.

Identifiants

pubmed: 30913100
doi: 10.1097/MAT.0000000000000972
pii: 00002480-202002000-00010
doi:

Substances chimiques

Biomarkers 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

166-172

Références

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Auteurs

Akihito Saito (A)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Eisuke Amiya (E)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Masaru Hatano (M)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Department of Therapeutic Strategy for Heart Failure, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Yasuyuki Shiraishi (Y)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Daisuke Nitta (D)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Shun Minatsuki (S)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Hisataka Maki (H)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Yumiko Hosoya (Y)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Masaki Tsuji (M)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Chie Bujo (C)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Kan Nawata (K)

Department of Cardiac Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Osamu Kinoshita (O)

Department of Cardiac Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Mitsutoshi Kimura (M)

Department of Cardiac Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Miyoko Endo (M)

Department of Organ Transplantation, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Yukie Kagami (Y)

Department of Organ Transplantation, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Mariko Nemoto (M)

Department of Organ Transplantation, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Yuichi Ikeda (Y)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Hiroyuki Morita (H)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Minoru Ono (M)

Department of Cardiac Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Issei Komuro (I)

From the Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

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