Genomic Testing for Human Health and Disease Across the Life Cycle: Applications and Ethical, Legal, and Social Challenges.
clinical utility
genetic disease
genomic data
genomic testing
genomics
healthcare
molecular diagnostics
public health
Journal
Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579
Informations de publication
Date de publication:
2019
2019
Historique:
received:
17
09
2018
accepted:
14
02
2019
entrez:
28
3
2019
pubmed:
28
3
2019
medline:
28
3
2019
Statut:
epublish
Résumé
The expanding use of genomic technologies encompasses all phases of life, from the embryo to the elderly, and even the posthumous phase. In this paper, we present the spectrum of genomic healthcare applications, and describe their scope and challenges at different stages of the life cycle. The integration of genomic technology into healthcare presents unique ethical issues that challenge traditional aspects of healthcare delivery. These challenges include the different definitions of utility as applied to genomic information; the particular characteristics of genetic data that influence how it might be protected, used and shared; and the difficulties applying existing models of informed consent, and how new consent models might be needed.
Identifiants
pubmed: 30915323
doi: 10.3389/fpubh.2019.00040
pmc: PMC6421958
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
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