Visual Assessment of Aqueous Humor Outflow.

anterior chamber aqueous humor optical coherence tomography optical imaging trabecular meshwork

Journal

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)
ISSN: 2162-0989
Titre abrégé: Asia Pac J Ophthalmol (Phila)
Pays: China
ID NLM: 101583622

Informations de publication

Date de publication:
27 Mar 2019
Historique:
entrez: 28 3 2019
pubmed: 28 3 2019
medline: 28 3 2019
Statut: aheadofprint

Résumé

In the past decade, many new pharmacological and surgical treatments have become available to lower intraocular pressure (IOP) for glaucoma. The majority of these options have targeted improving aqueous humor outflow (AHO). At the same time, in addition to new treatments, research advances in AHO assessment have led to the development of new tools to structurally assess AHO pathways and to visualize where aqueous is flowing in the eye. These new imaging modalities have uncovered novel AHO observations that challenge traditional AHO concepts. New behaviors including segmental, pulsatile, and dynamic AHO may have relevance to the disease and the level of therapeutic response for IOP-lowering treatments. By better understanding the regulation of segmental, pulsatile, and dynamic AHO, it may be possible to find new and innovative treatments for glaucoma aiming at these new AHO behaviors.

Identifiants

pubmed: 30916496
doi: 10.22608/APO.201911
pmc: PMC7028348
mid: NIHMS1065030
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NEI NIH HHS
ID : K08 EY024674
Pays : United States

Informations de copyright

Copyright 2019 Asia-Pacific Academy of Ophthalmology.

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Auteurs

Xiaobin Xie (X)

Eye Hospital of China Academy of Chinese Medical Sciences, Beijing, China.
UCLA Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA, United States.

Goichi Akiyama (G)

UCLA Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA, United States.

Thania Bogarin (T)

UCLA Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA, United States.

Sindhu Saraswathy (S)

UCLA Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA, United States.

Alex S Huang (AS)

UCLA Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA, United States.

Classifications MeSH