Concentric and Eccentric Pedaling-Type Interval Exercise on a Soft Robot for Stable Coronary Artery Disease Patients: Toward a Personalized Protocol.
cardiovascular rehabilitation
concentric and eccentric exercise
high-intensity interval training
muscle oxygen saturation
near-infrared spectroscopy
peak oxygen uptake
ramp test
skeletal muscle power
soft robot
Journal
JMIR research protocols
ISSN: 1929-0748
Titre abrégé: JMIR Res Protoc
Pays: Canada
ID NLM: 101599504
Informations de publication
Date de publication:
27 Mar 2019
27 Mar 2019
Historique:
received:
07
05
2018
accepted:
20
10
2018
revised:
18
10
2018
entrez:
28
3
2019
pubmed:
28
3
2019
medline:
28
3
2019
Statut:
epublish
Résumé
Cardiovascular diseases are the leading causes of death worldwide, and coronary artery disease (CAD) is one of the most common causes of death in Europe. Leading cardiac societies recommend exercise as an integral part of cardiovascular rehabilitation because it reduces the morbidity and mortality of patients with CAD. Continuous low-intensity exercise using shortening muscle actions (concentric, CON) is a common training modality during cardiovascular rehabilitation. However, a growing clinical interest has been recently developed in high-intensity interval training (HIIT) for stable patients with CAD. Exercise performed with lengthening muscle actions (eccentric, ECC) could be tolerated better by patients with CAD as they can be performed with higher loads and lower metabolic cost than CON exercise. We developed a clinical protocol on a soft robot to compare cardiovascular and muscle effects of repeated and work-matched CON versus ECC pedaling-type interval exercise between patients with CAD during cardiovascular rehabilitation. This study aims to ascertain whether the developed training protocols affect peak oxygen uptake (VO We will randomize 20-30 subjects to either the CON or ECC group. Both groups will perform a ramp test to exhaustion before and after the training period to measure cardiovascular parameters and SmO The first patients with CAD, who completed the training, showed protocol-specific improvements, reflecting, in part, the lower aerobic training status of the patient completing the CON protocol. Rehabilitation under the CON protocol, more than under the ECC protocol, improved cardiovascular parameters, that is, VO This study indicates the potential of the implemented CON and ECC protocols of pedaling-type interval exercise to improve oxygen metabolism of exercised muscle groups while maintaining or even increasing the P ClinicalTrials.gov NCT02845063; https://clinicaltrials.gov/ct2/show/NCT02845063.
Sections du résumé
BACKGROUND
BACKGROUND
Cardiovascular diseases are the leading causes of death worldwide, and coronary artery disease (CAD) is one of the most common causes of death in Europe. Leading cardiac societies recommend exercise as an integral part of cardiovascular rehabilitation because it reduces the morbidity and mortality of patients with CAD. Continuous low-intensity exercise using shortening muscle actions (concentric, CON) is a common training modality during cardiovascular rehabilitation. However, a growing clinical interest has been recently developed in high-intensity interval training (HIIT) for stable patients with CAD. Exercise performed with lengthening muscle actions (eccentric, ECC) could be tolerated better by patients with CAD as they can be performed with higher loads and lower metabolic cost than CON exercise.
OBJECTIVE
OBJECTIVE
We developed a clinical protocol on a soft robot to compare cardiovascular and muscle effects of repeated and work-matched CON versus ECC pedaling-type interval exercise between patients with CAD during cardiovascular rehabilitation. This study aims to ascertain whether the developed training protocols affect peak oxygen uptake (VO
METHODS
METHODS
We will randomize 20-30 subjects to either the CON or ECC group. Both groups will perform a ramp test to exhaustion before and after the training period to measure cardiovascular parameters and SmO
RESULTS
RESULTS
The first patients with CAD, who completed the training, showed protocol-specific improvements, reflecting, in part, the lower aerobic training status of the patient completing the CON protocol. Rehabilitation under the CON protocol, more than under the ECC protocol, improved cardiovascular parameters, that is, VO
CONCLUSIONS
CONCLUSIONS
This study indicates the potential of the implemented CON and ECC protocols of pedaling-type interval exercise to improve oxygen metabolism of exercised muscle groups while maintaining or even increasing the P
TRIAL REGISTRATION
BACKGROUND
ClinicalTrials.gov NCT02845063; https://clinicaltrials.gov/ct2/show/NCT02845063.
Identifiants
pubmed: 30916659
pii: v8i3e10970
doi: 10.2196/10970
pmc: PMC6456820
doi:
Banques de données
ClinicalTrials.gov
['NCT02845063']
Types de publication
Journal Article
Langues
eng
Pagination
e10970Informations de copyright
©Daniel P Fitze, Martino Franchi, Werner L Popp, Severin Ruoss, Silvio Catuogno, Karin Camenisch, Debora Lehmann, Christian M Schmied, David Niederseer, Walter O Frey, Martin Flück. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 27.03.2019.
Références
Med Sci Sports Exerc. 2000 Jan;32(1):70-84
pubmed: 10647532
Am J Physiol Regul Integr Comp Physiol. 2000 May;278(5):R1282-8
pubmed: 10801298
Cochrane Database Syst Rev. 2001;(1):CD001800
pubmed: 11279730
News Physiol Sci. 2001 Dec;16:256-61
pubmed: 11719600
J Orthop Sports Phys Ther. 2003 Oct;33(10):557-71
pubmed: 14620785
Eur J Cardiovasc Prev Rehabil. 2004 Jun;11(3):216-22
pubmed: 15179103
Am J Cardiol. 2005 May 1;95(9):1080-4
pubmed: 15842976
N Engl J Med. 2005 Apr 21;352(16):1685-95
pubmed: 15843671
Circulation. 2005 Aug 9;112(6):924-34
pubmed: 16087812
J Physiol. 1939 Jun 14;96(1):45-64
pubmed: 16995114
Circulation. 2007 Jun 19;115(24):3086-94
pubmed: 17548726
J Biomed Opt. 2010 Jan-Feb;15(1):017008
pubmed: 20210482
Med Sci Sports Exerc. 2011 Aug;43(8):1465-73
pubmed: 21228724
Philos Trans A Math Phys Eng Sci. 2011 Nov 28;369(1955):4577-90
pubmed: 22006907
Exerc Sport Sci Rev. 2012 Jan;40(1):4-12
pubmed: 22016147
J Physiol. 2012 Mar 1;590(5):1077-84
pubmed: 22289907
Eur J Prev Cardiol. 2012 Oct;19(5):1005-33
pubmed: 22637741
Sports Med. 2012 Jul 1;42(7):587-605
pubmed: 22694349
Circ J. 2013;77(2):281-92
pubmed: 23328449
Med Sci Sports Exerc. 2013 Aug;45(8):1436-42
pubmed: 23470301
Sports Med. 2013 Jun;43(6):483-512
pubmed: 23657934
J Appl Physiol (1985). 2014 Jun 1;116(11):1426-34
pubmed: 23823152
Eur J Appl Physiol. 2014 Feb;114(2):405-17
pubmed: 24327174
Med Sci Sports Exerc. 2014 Nov;46(11):2062-9
pubmed: 24621961
Eur J Appl Physiol. 2016 Apr;116(4):673-85
pubmed: 26759155
Can J Cardiol. 2016 Apr;32(4):485-94
pubmed: 26927863
Biogerontology. 2016 Jun;17(3):567-80
pubmed: 26936444
Ann Phys Rehabil Med. 2017 Jan;60(1):50-57
pubmed: 27346629
Eur Heart J. 2016 Nov 7;37(42):3232-3245
pubmed: 27523477
Atherosclerosis. 2016 Sep;252:207-274
pubmed: 27664503
Front Physiol. 2016 Nov 16;7:483
pubmed: 27899894
Front Physiol. 2017 Feb 28;8:120
pubmed: 28293200
Front Physiol. 2017 Jul 04;8:447
pubmed: 28725197
Front Physiol. 2017 Aug 31;8:640
pubmed: 28912726
J Appl Physiol Respir Environ Exerc Physiol. 1981 Jan;50(1):217-21
pubmed: 6782055
J Am Coll Cardiol. 1994 Feb;23(2):358-63
pubmed: 8294687
JAMA. 1996 Jul 17;276(3):205-10
pubmed: 8667564
J Physiol. 1976 Sep;260(2):267-77
pubmed: 978517