Associations between Adipokines in Arthritic Disease and Implications for Obesity.
adipokines
obesity
osteoarthritis
rheumatoid arthritis
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
26 Mar 2019
26 Mar 2019
Historique:
received:
04
03
2019
revised:
18
03
2019
accepted:
21
03
2019
entrez:
29
3
2019
pubmed:
29
3
2019
medline:
10
7
2019
Statut:
epublish
Résumé
Secretion from adipose tissue of adipokines or adipocytokines, comprising of bioactive peptides or proteins, immune molecules and inflammatory mediators, exert critical roles in inflammatory arthritis and obesity. This review considers the evidence generated over the last decade regarding the effects of several adipokines including leptin, adiponectin, visfatin, resistin, chemerin and apelin, in cartilage and bone homeostasis in the pathogenesis of rheumatoid arthritis and osteoarthritis, which has important implications for obesity.
Identifiants
pubmed: 30917508
pii: ijms20061505
doi: 10.3390/ijms20061505
pmc: PMC6471239
pii:
doi:
Substances chimiques
Adipokines
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : The National Science Council of Taiwan
ID : MOST 107-2314-B-039-064-
Organisme : The National Science Council of Taiwan
ID : MOST107-2320-B-039-019-MY3
Organisme : The National Science Council of Taiwan
ID : MOST 105-2320-B-039-015-MY3
Organisme : China Medical University, Taichung, Taiwan
ID : CMU107-BC-5
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